Cryobiopsy Versus Forceps Biopsy for Pulmonary Lesions



Status:Recruiting
Healthy:No
Age Range:18 - Any
Updated:1/31/2019
Start Date:November 2016
End Date:July 2021
Contact:David M DiBardino, MD
Email:david.dibardino@uphs.upenn.edu
Phone:215-615-0359

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

An Un-blinded, Intra-patient Comparison of Transbronchial Forceps Biopsy and Cryobiopsy for Peripheral Pulmonary Lesions

Purpose: Patients with peripheral lung nodules require evaluation for lung cancer. Our aim is
to assess the diagnostic yield of a new technique, transbronchial cryobiopsies, in patients
at risk for lung cancer. Target population: Patients referred for bronchoscopy and lung
biopsies as a part of their work up for peripheral lung lesions. Procedures: Patients
enrolled will have forceps transbronchial biopsies followed by transbronchial cryobiopsies
for their lung lesion during bronchoscopy.


Inclusion Criteria:

1. Age >/= 18

2. At least one 10-40 mm peripheral lung lesion documented on CTscan referred for
diagnostic bronchoscopy

3. Subject is able to undergo informed consent

Exclusion Criteria:

1. Coagulopathy (platelet count < 50,000, INR > 1.5) detected on blood testing done
within 3 weeks of the procedural visit

2. Lesion associated with a prominent vessel evident on CT scan

3. Pure ground glass lesion

4. Fibrotic interstitial lung abnormalities on chest CT

5. Bullous emphysema in region of nodule

6. Supplemental oxygen utilization at baseline

7. BMI > 40

8. End stage renal disease
We found this trial at
1
site
Univ of Pennsylvania
3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Phone: 215-615-0359
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials