Study of Pharmacokinetics, Efficacy and Safety of a Recombinant and Protein-Free Factor VIII (rAHF-PFM) in Hemophilia A Patients - A Continuation of Clinical Study 069901

Inclusion Criteria:

- Subject has completed Baxter protocol 069901

- Subject is HIV-1 seronegative or, if HIV-1 seropositive, has a CD4+ lymphocyte count
>= 400/mm3 documented within three months of the screening visit

- Subject (and his legally acceptable representative, in the case of study participants
>= 10 and < 18 years of age) has been informed of the nature of the study, agreed to
its provisions, and signed and dated the informed consent form approved by the
appropriate IRB/IEC and Baxter

Exclusion Criteria:

- The subject received factor VIII products other than rAHF-PFM upon completion of
Baxter protocol 069901

- The subject developed an inhibitor to factor VIII, measured in the central laboratory,
during Baxter protocol 069901. An inhibitor is defined as a Bethesda titer > 1.0 or,
if Bethesda titer < 1.0, confirmation using the Nijmegen modification of the Bethesda
assay with a titer > 0.6

- The subject is scheduled to receive an immunomodulating drug other than
anti-retroviral chemotherapy (e.g., a-interferon, steroids) during the course of the
study

- The subject is identified by the investigator as being unable or unwilling to
cooperate with study procedures