Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy For Locally Advanced Breast Cancer



Status:Recruiting
Conditions:Breast Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:10/6/2018
Start Date:August 17, 2017
End Date:August 2020
Contact:Andrea Barrio, MD
Email:barrioa@mskcc.org
Phone:646-888-5117

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Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Patients Presenting With Locally Advanced Breast Cancer: A Prospective Study

This study is being done to help the investigators determine how accurate the sentinel lymph
node biopsy (SLNB) procedure is in identifying residual cancer cells after neoadjuvant
chemotherapy in patients presenting with locally advanced breast cancer.


Inclusion Criteria:

- Female patients over 18 years of age with biopsy-proven breast cancer

- Patients presenting with locally advanced disease in the breast (cT4) and/or in the
nodes (cN2/N3) as assessed by clinical exam and imaging

- Patients presenting to surgery clinic after receipt of NAC at outside hospital with
documentation of cT4 or cN2/3 disease on initial outside physical exam and imaging
studies

- Patients receiving NAC and having a nodal complete clinical response as assessed by
physical exam

Exclusion Criteria:

- Patients with a prior history of ipsilateral breast cancer

- Pregnant patients

- Patients with persistent palpable axillary nodes after NAC, as assessed by physical
exam

- Patients not consenting to ALND
We found this trial at
7
sites
1275 York Ave
New York, New York 10021
(212) 639-2000
Principal Investigator: Andrea Barrio, MD
Phone: 646-888-5117
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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Middletown, New Jersey 07748
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225 Summit Avenue
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1000 North Village Avenue
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