Plant Based Diet, Ethnicity, and the Gut Microbiome
| Status: | Recruiting |
|---|---|
| Conditions: | Infectious Disease |
| Therapuetic Areas: | Immunology / Infectious Diseases |
| Healthy: | No |
| Age Range: | 18 - 40 |
| Updated: | 10/18/2018 |
| Start Date: | August 25, 2017 |
| End Date: | March 30, 2019 |
| Contact: | Heidi J Silver, Ph.D. |
| Email: | heidi.j.silver@vanderbilt.edu |
| Phone: | 6158759355 |
Samples will be collected to determine human genetic variation, fecal and oral microbial
communities, and metabolome products. Several evolutionary and ecological diversity metrics
will be distilled to test: a) if microbiome variation within each ethnicity is less than that
between ethnicities; b) if microbiome variation is finely structured according to genetic
relatedness; and c) if dietary variation impacts human genome x microbiome associations.
communities, and metabolome products. Several evolutionary and ecological diversity metrics
will be distilled to test: a) if microbiome variation within each ethnicity is less than that
between ethnicities; b) if microbiome variation is finely structured according to genetic
relatedness; and c) if dietary variation impacts human genome x microbiome associations.
To characterize the human gut microbiome under highly controlled dietary intake in healthy
normal weight adult participants who differ by ethnicity: White non-Hispanic and Black
non-Hispanic adults. Samples will be collected to determine human genetic variation, fecal
and oral microbial communities, and metabolome products. Several evolutionary and ecological
diversity metrics will be distilled to test: a) if microbiome variation within each ethnicity
is less than that between ethnicities; b) if microbiome variation is finely structured
according to genetic relatedness; and c) if dietary variation impacts human genome x
microbiome associations.
normal weight adult participants who differ by ethnicity: White non-Hispanic and Black
non-Hispanic adults. Samples will be collected to determine human genetic variation, fecal
and oral microbial communities, and metabolome products. Several evolutionary and ecological
diversity metrics will be distilled to test: a) if microbiome variation within each ethnicity
is less than that between ethnicities; b) if microbiome variation is finely structured
according to genetic relatedness; and c) if dietary variation impacts human genome x
microbiome associations.
Inclusion Criteria:
- Female
- Age 18-40
- BMI 18.5-24.9
- Caucasian or African American
Exclusion Criteria:
- Not weight stable
- Using Medications
- Using Dietary Supplements
- Chronic Disease
- Tobacco Use
- Drug Use
- Pregnant or Lactating
- Diet Restrictions
- Vegetarian or Vegan
We found this trial at
1
site
1211 Medical Center Dr
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-5000
Phone: 615-936-0365
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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