A Comparison of Analgesic Efficacy of Ultrasound-Guided Genicular Nerve Block Versus Saline Injection for Total Knee Replacement
| Status: | Recruiting |
|---|---|
| Conditions: | Post-Surgical Pain, Orthopedic |
| Therapuetic Areas: | Musculoskeletal, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 40 - 85 |
| Updated: | 10/22/2017 |
| Start Date: | October 5, 2017 |
| End Date: | October 5, 2020 |
| Contact: | Antoun M Nader, MD |
| Email: | a-nader@northwestern.edu |
| Phone: | (312) 695-2500 |
A Comparison of Analgesic Efficacy of Ultrasound-Guided Genicular Nerve Block Versus Saline Injection for Total Knee Replacement: a Prospective, Randomized Controlled Trial
Do ultrasound-guided genicular nerve blocks with 0.5% bupivacaine provide improved knee
analgesia for patients recovering from total knee replacement surgery compared to saline
injection?
Hypotheses:
The investigators hypothesize that the combination of ultrasound-guided adductor canal block
(ACB) and genicular nerve block will achieve lower opioid consumption and therefore lead to
decreased systemic side effects and improved overall satisfaction compared to
ultrasound-guided saline injection for patients undergoing minimally invasive elective total
knee arthroplasty (TKA).
analgesia for patients recovering from total knee replacement surgery compared to saline
injection?
Hypotheses:
The investigators hypothesize that the combination of ultrasound-guided adductor canal block
(ACB) and genicular nerve block will achieve lower opioid consumption and therefore lead to
decreased systemic side effects and improved overall satisfaction compared to
ultrasound-guided saline injection for patients undergoing minimally invasive elective total
knee arthroplasty (TKA).
Inclusion Criteria:
- Participants 40 to 85 years old who are presenting for minimally invasive total knee
arthroplasty under spinal anesthesia and are candidates for peripheral nerve blocks.
- Minimally invasive is defined as custom modified instrumentation, a quadriceps sparing
arthrotomy that does not extend beyond 1cm proximal to the patella and surgical
techniques that focus on soft tissue protection.
Exclusion Criteria:
- Patient refusal
- American Society of Anesthesiologists physical status classification of 4 or higher
- Pre-existing neuropathy in the femoral or sciatic distribution
- Coagulopathy
- Infection at the site
- Chronic opioid use (greater than 3 months)
- Pregnancy
- Medical conditions limiting physical therapy participation
- Any other contra-indication to regional anesthesia
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