A Safety and Pharmacokinetics Study in Participants With Rheumatoid Arthritis



Status:Completed
Conditions:Arthritis, Rheumatoid Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:18 - 75
Updated:2/8/2019
Start Date:November 2005
End Date:November 2007

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A Phase 1b/2 Multiple-Dose Safety Study and Pharmacokinetic/ Pharmacodynamic Study of LY2189102 in Patients With Rheumatoid Arthritis

The purpose of this study is to examine the safety and efficacy of this antibody in
participants with rheumatoid arthritis.

Part A of the study is an initial dose escalation phase

Part B of the study is a randomized allocation of the entire dosing group to parallel
treatment assignments


Inclusion Criteria:

- diagnosis of rheumatoid arthritis

- regular use of methotrexate

- active rheumatoid arthritis

Exclusion Criteria:

- Juvenile Rheumatoid Arthritis

- evidence of tuberculosis

- women who are pregnant or become pregnant during study, or are breast-feeding
We found this trial at
11
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Miami, FL
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Albuquerque, NM
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Bend, OR
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Bialystok,
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Mayfield, OH
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Meridian, ID
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Orangeburg, SC
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Port Orange, FL
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Tucson, AZ
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Upland, CA
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Vero Beach, FL
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