Adherence and Outcome of Upper Airway Stimulation (UAS) for OSA International Registry

Inspire intends to conduct this registry to: 1) collect Inspire therapy clinical evidence in
the clinical practice setting; 2) collect additional information on the effectiveness, use
and safety in the commercial setting; and 3) engage physician customers to report the
collective outcome within a group of properly trained programs that utilize Inspire therapy
on a regular basis.

In addition, a sub-study will be conducted under this Registry at a limited number of
Registry centers and will include a cohort of Registry patients and a cohort of patients who
have not received the Inspire therapy device due to denial of insurance coverage. The two
sub-study cohorts' quality of life and AHI data will be compared.