Articaine vs Lidocaine for Pediatric Dental Procedures
| Status: | Not yet recruiting |
|---|---|
| Conditions: | Post-Surgical Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 4 - 11 |
| Updated: | 3/21/2019 |
| Start Date: | April 2019 |
| End Date: | December 2020 |
| Contact: | Athanasios Zavras, DDS DdMedSc |
| Email: | zavras@bu.edu |
| Phone: | 617-638-5023 |
Efficacy of Articaine vs. Lidocaine When Used for Local Infiltration in Pediatric Dental Procedures
The purpose of this study is to compare the efficacy of two types of local anesthesia
(articaine and lidocaine) for infiltration anesthesia during restorative dental procedures on
lower teeth in pediatric patients. The patients will require similar dental operative
procedures on both right and left sides of the mandible in order to qualify for this study.
The study will require at least two dental appointments, where a randomized, cross-over study
methodology will be utilized. All subjects will be treated by the same dentist. The comfort
of the patient will be assessed at various points during the procedure using the Wong-Baker
Faces Scale.
(articaine and lidocaine) for infiltration anesthesia during restorative dental procedures on
lower teeth in pediatric patients. The patients will require similar dental operative
procedures on both right and left sides of the mandible in order to qualify for this study.
The study will require at least two dental appointments, where a randomized, cross-over study
methodology will be utilized. All subjects will be treated by the same dentist. The comfort
of the patient will be assessed at various points during the procedure using the Wong-Baker
Faces Scale.
This study will compare articaine to lidocaine with overall quality of anesthesia. When
administering lidocaine, the investigator will follow standard of care by administering a
buccal infiltration injection followed by 2-3 interpapillary injections, one at each gingival
papilla where the rubber dam clamp will be placed and possibly more if needed in areas where
dental treatment will be provided. A single buccal infiltration injection of articaine will
be administered, with the hypothesis that articaine is a stronger anesthestic and will
deliver palatal anesthesia with a single injection, eliminating the interpapillary injections
required for lidocaine to achieve adequate soft tissue anesthesia. The comfort of the patient
during multiple steps of the dental treatment will be recorded. A randomized, cross-over
methodology will be used. This study seeks to find whether adequate anesthesia in the
mandible can be achieved with a single injection of articaine in the buccal aspect of the jaw
instead of having to administer multiple injections of lidocaine, which can increase patient
anxiety and discomfort. By decreasing the number of injections needed for children during
dental treatment while providing adequate local anesthesia, dentists can provide more
comfortable care to their pediatric patients.
Specific Aims/ Hypothesis
Specific Aim 1: To compare articaine to lidocaine with achieving effective local anesthesia
in the mandible of pediatric dental patients.
Hypothesis: The solubility of articaine will provide more effective anesthetic delivery
through the soft and hard tissue of the mandible following buccal infiltration, eliminating
the need for multiple injections.
Specific Aim 2: To identify which type of anesthetic provides the best patient experience by
way of measuring patient comfort at various stages of the dental procedure.
Hypothesis: The patient will have an equally comfortable experience during the dental
procedure when articaine or lidocaine is used.
administering lidocaine, the investigator will follow standard of care by administering a
buccal infiltration injection followed by 2-3 interpapillary injections, one at each gingival
papilla where the rubber dam clamp will be placed and possibly more if needed in areas where
dental treatment will be provided. A single buccal infiltration injection of articaine will
be administered, with the hypothesis that articaine is a stronger anesthestic and will
deliver palatal anesthesia with a single injection, eliminating the interpapillary injections
required for lidocaine to achieve adequate soft tissue anesthesia. The comfort of the patient
during multiple steps of the dental treatment will be recorded. A randomized, cross-over
methodology will be used. This study seeks to find whether adequate anesthesia in the
mandible can be achieved with a single injection of articaine in the buccal aspect of the jaw
instead of having to administer multiple injections of lidocaine, which can increase patient
anxiety and discomfort. By decreasing the number of injections needed for children during
dental treatment while providing adequate local anesthesia, dentists can provide more
comfortable care to their pediatric patients.
Specific Aims/ Hypothesis
Specific Aim 1: To compare articaine to lidocaine with achieving effective local anesthesia
in the mandible of pediatric dental patients.
Hypothesis: The solubility of articaine will provide more effective anesthetic delivery
through the soft and hard tissue of the mandible following buccal infiltration, eliminating
the need for multiple injections.
Specific Aim 2: To identify which type of anesthetic provides the best patient experience by
way of measuring patient comfort at various stages of the dental procedure.
Hypothesis: The patient will have an equally comfortable experience during the dental
procedure when articaine or lidocaine is used.
Inclusion Criteria:
- patients receiving dental care at Boston Medical Center Pediatric Dental Clinic,
Boston University Pediatric Oral Health Center, and East Boston Neighborhood Health
Center Pediatric Dental Clinic
- patients needing similar restorative dental procedures to primary molar teeth on both
sides of the maxillary arch
- boys and girls between ages 4 to 11 years
- English speaking and be able to understand verbal assent.
Exclusion Criteria:
- patients for whom the use of articaine is contraindicated such as patients with
Acetylcholine esterase deficiency
- patients for whom the use of lidocaine is contraindicated in patients taking
metronidazole
We found this trial at
1
site
100 East Newton Street
Boston, Massachusetts 02118
Boston, Massachusetts 02118
Phone: 617-638-5023
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