Understanding Hemophilia A and B Drug Dosage Administration Patterns

Study recruitment was stopped due to difficulty in enrolling the targeted number of patients
on March 21, 2018. Subjects currently enrolled into the study have completed the study as per
protocol. There were no safety concerns involved in the decision to stop enrollment.

Physician/Clinician Participants:

- Must be a healthcare provider

- Currently manages at least 10 hemophilia A and/or B patients

Patient Participants:

- Willing and able to provide informed consent

- Diagnosed with hemophilia A or B

- Current disease severity is either moderately severe or severe with a clotting factor
level of ≤5%

- If suffering from hemophilia A, must be currently taking moroctocog alfa (or another
standard half-life treatment), rurioctocog alfa or efraloctocog alfa for at least six
months.

(If currently taking rurioctocog alfa or efraloctocog alfa, must have been switched from a
standard half-life treatment and had been on that prior treatment for at least six months).

- If suffering from hemophilia B, must be currently taking nonacog alfa or eftrenonacog
alfa for at least six months (If currently taking eftrenonacog alfa, must have
switched from nonacog alfa and had been on that prior treatment for at least six
months).

- Infuse at least 3 times per month

Exclusion criteria:

- Female with hemophilia A or B

- Mild Haemophilia A or B