Comparison of Cardiorespiratory Fitness Among Regular Exercisers With and Without Parkinson Disease and Across Different Modes of Group Exercise
| Status: | Completed |
|---|---|
| Conditions: | Parkinsons Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | 55 - 75 |
| Updated: | 10/28/2017 |
| Start Date: | September 2015 |
| End Date: | June 2017 |
The central goal of the proposed study is to generate essential pilot data necessary to
support an established line of research leading to future extramural grant submissions. The
aims of the current study are two-fold: 1) to compare cardiorespiratory fitness (CRF) and
gait endurance across three groups of people: (1) individuals with Parkinson Disease (PD) who
participate in boxing on a regular basis, (2) individuals with PD who participate in exercise
other than boxing on a regular basis and (3) healthy controls of the same age who exercise on
a regular basis and 2) to examine the relationship between CRF and motor symptoms of PD
(bradykinesia, tremor and postural instability). Forty-five participants (15 for each group)
who participate in exercise on a regular basis (at least 120 minutes of exercise per week for
the past 3 months) will be recruited for this cross-sectional study. In a single testing
session, participants will perform the following tests: (1) clinical performance measures and
(2) a CRF assessment. A one-way ANOVA with appropriate post hoc tests will be used to examine
differences in dependent variables across the three exercise groups. Relationships between
CRF and clinical performance measures will be evaluated with Pearson's correlation
coefficients.
support an established line of research leading to future extramural grant submissions. The
aims of the current study are two-fold: 1) to compare cardiorespiratory fitness (CRF) and
gait endurance across three groups of people: (1) individuals with Parkinson Disease (PD) who
participate in boxing on a regular basis, (2) individuals with PD who participate in exercise
other than boxing on a regular basis and (3) healthy controls of the same age who exercise on
a regular basis and 2) to examine the relationship between CRF and motor symptoms of PD
(bradykinesia, tremor and postural instability). Forty-five participants (15 for each group)
who participate in exercise on a regular basis (at least 120 minutes of exercise per week for
the past 3 months) will be recruited for this cross-sectional study. In a single testing
session, participants will perform the following tests: (1) clinical performance measures and
(2) a CRF assessment. A one-way ANOVA with appropriate post hoc tests will be used to examine
differences in dependent variables across the three exercise groups. Relationships between
CRF and clinical performance measures will be evaluated with Pearson's correlation
coefficients.
Inclusion Criteria:
- All participants included in this study must be between the ages of 55 and 75
- Be able to ambulate independently without physical assistance, assistive device, or
lower extremity orthosis
- Be able to follow at least 3-step verbal commands
- Participate in a community-based group exercise program
- Be classified as regular exercisers by participating in 120 minutes per week for at
least 3 months
- And have a physician's consent to undergo a graded exercise test (GXT).
- Furthermore, only participants that are identified as low or moderate risk for
cardiovascular disease based on ACSM's risk stratification guidelines will be included
in the study.
- Participants for the two PD groups must have a diagnosis of idiopathic PD
- Have a Hoehn-Yahr score of 1, 2, or 3
- And either participate regularly in boxing training at Rock Steady Boxing or
participate in another community-based group exercise program on a regular basis,
classified as 120 minutes per week for at least 3 months.
Exclusion Criteria:
- Participants may not be included in the study if they have had any surgery in the past
6 months
- Current musculoskeletal or complications from other health issues that influence
walking.
- The participants without disability cannot be involved in the study if they have any
preexisting neurological conditions.
- Participants with PD cannot be involved in the study if they have preexisting
neurological conditions other than idiopathic PD (e.g. no diagnosis of Parkinson Plus
syndrome), past brain surgery or implantation of a deep brain stimulator.
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