Study to Evaluate Effects of Probenecid, Rifampin and Verapamil on Bexagliflozin in Healthy Subjects

Inclusion Criteria:

1. Subjects with body-mass index (BMI) between 18.0 kg/m2 and 32.0 kg/m2

2. Subjects who have not used tobacco for at least 3 months before screening

3. Subjects who are willing to use an adequate form of birth control during the study and
for 30 days after discharge from clinic

4. Subjects who are willing and able to be confined to the clinical research facility as
required by the protocol

Exclusion Criteria:

1. Subjects with a clinically significant history of allergy to drugs or latex

2. Subjects with a history of alcohol or drug dependence in the past 12 months.

3. Subjects who have donated a significant amount of blood in the past 2 months

4. Female subjects who are pregnant or breastfeeding

5. Subjects who have taken an investigational drug in the past 30 days or 7 half-lives of
the investigational drug, whichever is longer

6. Subjects who had previously taken probenecid, rifampin or verapamil within 3 months of
screening