Long-Term Quality of Life in Patients With Metastatic Melanoma Treated With Checkpoint Inhibitors



Status:Active, not recruiting
Conditions:Skin Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:2/8/2019
Start Date:October 25, 2017
End Date:October 2020

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To identify and describe long-term quality of life (QOL) issues in patients with metastatic
melanoma treated with checkpoint inhibitors who achieved cancer control for a minimum of 12
months and remain on maintenance checkpoint inhibitor therapy.


Inclusion Criteria:

- Be able to speak and read English

- Be able to provide informed consent

- Have been diagnosed with metastatic melanoma at age 18 years or older

- Have been treated with either single agent or combination checkpoint inhibitor

- Be at least 12 months since first dose of above named agents

- Received no other systemic therapy after initiation of immunotherapy (interval
radiation or surgery will be permitted based on review with primary treating medical
oncologist)

Exclusion Criteria:

- Patients with cognitive, visual, or motor impairment such that they cannot complete
the survey as assessed by the research or clinical team

- Patients who developed a subsequent cancer after starting on checkpoint inhibitor(s),
exclusive of non-melanoma superficial skin cancers

- Patients with clinical documentation of progressive disease on the most recent
assessment in the electronic medical record

- Patients with symptomatic progression but continue on immunotherapy

- Note: For any patients where the disease status is not clear, we will confirm
that the disease is either stable or responsive with their primary treating
medical oncologist
We found this trial at
6
sites
136 Mountainview Boulevard
Basking Ridge, New Jersey 07920
Phone: 646-888-8147
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Commack, New York 11725
Phone: 646-888-8147
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Commack, NY
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500 Westchester Avenue
Harrison, New York 10604
Phone: 646-888-8147
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Harrison, NY
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480 Red Hill Road
Middletown, New Jersey 07748
Phone: 646-888-8147
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1275 York Ave
New York, New York 10021
(212) 639-2000
Principal Investigator: Deborah Korenstein, MD
Phone: 646-888-8147
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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Rockville Centre, New York 11570
Phone: 646-888-8147
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Rockville Centre, NY
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