Memory Study of Youngest Women Enrolled in the Women's Health Initiative Hormone Therapy (HT) Arm



Status:Completed
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:50 - 54
Updated:11/8/2017
Start Date:June 2009
End Date:June 2016

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Women's Health Initiative Memory Study of Younger Women

WHIMS-Y provides valuable information on the long-term effects on risk of cognitive
impairment of hormone therapy in a subset of WHI participants in the WHI Hormone Trials.
Following cessation of study-prescribed HT cognitive function and impairment were assessed.

The Women's Health Initiative Memory Study of Younger Women (WHIMS-Y) is proposed to assess
the long-term impact of random assignment to postmenopausal hormone therapy (equine estrogen
alone or in combination with medroxyprogesterone versus placebo) among women who were aged
50-54 at the time of randomization into the WHI hormone trials. Secondary objectives relate
to the consistency of any treatment effects across unopposed or opposed therapy and whether
there exists evidence of graded relationships between cognitive effects and age of
administration, years from menopause, and baseline risk factors for cognitive impairment.

Inclusion Criteria:

- Must be enrolled in the Women's Health Initiative Extension

Exclusion Criteria:

- Not enrolled in the Women's Health Initiative Extension
We found this trial at
1
site
1 Medical Center Blvd
Winston-Salem, North Carolina 27157
336-716-2011
Wake Forest University Health Sciences Welcome to Wake Forest Baptist Medical Center, a fully integrated...
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from
Winston-Salem, NC
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