Minimizing the Utilization of Voiding Cystourethrography for Patients With Antenatal Hydronephrosis
Status: | Recruiting |
---|---|
Conditions: | Nephrology |
Therapuetic Areas: | Nephrology / Urology |
Healthy: | No |
Age Range: | Any - 5 |
Updated: | 11/8/2017 |
Start Date: | July 27, 2016 |
End Date: | June 2021 |
Contact: | Nora Kern, M.D. |
Email: | NGL2Z@virginia.edu |
Phone: | 434-924-0236 |
It has previously been found that there is no correlation between degree of hydronephrosis
and presence of reflux; however this is oftentimes the criteria physicians use to obtain a
VCUG.
and presence of reflux; however this is oftentimes the criteria physicians use to obtain a
VCUG.
Investigators conducted a previous retrospective study to evaluate other possible findings on
ultrasound that may better predict reflux. Investigators found that if a postnatal ultrasound
showed any of the three findings of hydroureter, duplication or dysmorphic kidney, then the
odds ratio of detecting reflux was 8.07 (95%CI 3.86, 16.87). The purpose of this study is to
perform a randomized prospective study to validate this retrospective study. Investigators
hypothesis is that patients with hydronephrosis alone will be more likely to have negative
VCUG studies; hence obtaining a VCUG for this indication may not be warranted.
ultrasound that may better predict reflux. Investigators found that if a postnatal ultrasound
showed any of the three findings of hydroureter, duplication or dysmorphic kidney, then the
odds ratio of detecting reflux was 8.07 (95%CI 3.86, 16.87). The purpose of this study is to
perform a randomized prospective study to validate this retrospective study. Investigators
hypothesis is that patients with hydronephrosis alone will be more likely to have negative
VCUG studies; hence obtaining a VCUG for this indication may not be warranted.
Inclusion Criteria:
- Patients with a history of antenatal hydronephrosis who have a post-natal ultrasound
demonstrating hydronephrosis alone and no other abnormalities
Exclusion Criteria:
- Patients with a post-natal ultrasound demonstrating bilateral hydronephrosis
- Patients with a history of posterior urethral valve or when a valve is suspected
- Patients who have hydronephrosis on ultrasound as well as other findings including
duplication, hydroureter, dysmorphic kidneys, or bladder abnormalities
We found this trial at
1
site
1221 Lee Street
Charlottesville, Virginia 22908
Charlottesville, Virginia 22908
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