Subarachnoid Hemorrhage Recovery And Galantamine

Inclusion Criteria:

- Spontaneous subarachnoid hemorrhage

- Presentation to hospital within 72 hours of symptoms

- Fisher grade 3 hemorrhage (thick subarachnoid clot) on initial computed tomography
(CT) scan

- Hunt and Hess grade 1-5 at time of randomization

- Presence of a cerebral aneurysm on computed tomographic angiography (CTA) or Angiogram
for which clipping or coiling is possible

- Ability to obtain medication within 36 hours of presentation

Exclusion Criteria:

- subarachnoid hemorrhage (SAH) due to causes other than aneurysm rupture (trauma,
arteriovenous malformation (AVM), mycotic aneurysms, Moyamoya)

- Pre-existing disability with modified Rankin Scale (mRS) score ≥2,

- Renal disease as defined by creatinine clearance less than 9 milliliters/min

- History of severe hepatic impairment (Child-Pugh score of 10-15)

- History of chronic obstructive pulmonary disease (COPD) or asthma

- History of dementia

- Co-morbid conditions likely to complicate therapy, including clinically significant
arrhythmia, acquired immune deficiency syndrome (AIDS), autoimmune disease,
malignancy, and expected mortality within 72 hours

- Expected mortality within 72 hours as determined by PI, treating neurointensivist and
neurosurgeon. (Clinically manifested by no attempt at securing aneurysm)

- Females who are pregnant.