The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients
| Status: | Completed |
|---|---|
| Conditions: | Ocular |
| Therapuetic Areas: | Ophthalmology |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 8/11/2018 |
| Start Date: | September 2016 |
| End Date: | October 2017 |
The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients, Pressure Control and Pupil Effects
This an interventional study looking at two different sequences of pre-operative eye drops,
to determine which order is more effective in reducing intraocular pressure with pupil
dilation.
to determine which order is more effective in reducing intraocular pressure with pupil
dilation.
Twenty healthy participants will be separated into two groups of 10 volunteers each. In both
groups, the participant's right eye will serve as a control with only
Tropicamide/phenylephrine given. In one group of 10 participants the left eyes will receive
Alphagan prior to Tropicamide/phenylephrine. In the other group of 10 eyes, the left eyes
will have Tropicamide/phenylephrine administered prior to Alphagan. The investigator will
observe the intraocular benefits of the addition of Alphagan over the
Tropicamide/phenylephrine alone and determine if pre-treating is any better than
post-treating. In addition, the investigator will monitor pupil response, as it is known that
Alphagan may have some effect on the pupil dilation.
groups, the participant's right eye will serve as a control with only
Tropicamide/phenylephrine given. In one group of 10 participants the left eyes will receive
Alphagan prior to Tropicamide/phenylephrine. In the other group of 10 eyes, the left eyes
will have Tropicamide/phenylephrine administered prior to Alphagan. The investigator will
observe the intraocular benefits of the addition of Alphagan over the
Tropicamide/phenylephrine alone and determine if pre-treating is any better than
post-treating. In addition, the investigator will monitor pupil response, as it is known that
Alphagan may have some effect on the pupil dilation.
Inclusion Criteria:
- Healthy with no major medical conditions. Contact lens wear is ok but must be not worn
on the day of the study
Exclusion Criteria:
- Diabetic, history of glaucoma
- history of iris trauma
- history of eye surgery except LASIK or Photorefractive keratectomy laser eye surgery
- Anisocoria
- pregnancy
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