A Phase 2 Study Evaluating The Efficacy And Safety Of PF 04494700 In Mild To Moderate Alzheimer's Disease



Status:Completed
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:50 - Any
Updated:12/2/2018
Start Date:December 2007
End Date:December 2010

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Double Blind, Placebo Controlled, Randomized, Multicenter Study Evaluating The Efficacy And Safety Of Eighteen Months Of Treatment With PF 04494700 (TTP488) In Participants With Mild To Moderate Alzheimer's Disease

The purpose of this study is to evaluate the efficacy and safety of PF 04494700 in
participants with mild to moderate Alzheimer's disease.


Inclusion Criteria:

- Mini Mental State Exam (MMSE) score between 14-26 (inclusive) at screening.

- Participants must be receiving acetylcholinesterase inhibitors on a stable dose for at
least 4 months prior to randomization

Exclusion Criteria:

- Current evidence or history of neurological, psychiatric and any other illness that
could contribute to non-Alzheimer's dementia.

- Known history of familial AD or any evidence for early onset AD known or possibly
associated with genetic mutations.

- Evidence or history of diabetes mellitus Type 1 or Type 2.

- History or symptoms of autoimmune disorders.
We found this trial at
43
sites
Pfizer Investigational Site
Vista, California 92083
?
mi
from
Vista, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Ann Arbor, Michigan 48109
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Pfizer Investigational Site
Atlanta, Georgia 30309
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Pfizer Investigational Site
Baltimore, Maryland 21234
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Pfizer Investigational Site
Beachwood, Ohio 44122
?
mi
from
Beachwood, OH
Click here to add this to my saved trials
Pfizer Investigational Site
Boston, Massachusetts 02115
?
mi
from
Boston, MA
Click here to add this to my saved trials
Pfizer Investigational Site
Charleston, South Carolina 29425
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Pfizer Investigational Site
Chicago, Illinois 60611
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Pfizer Investigational Site
Dallas, Texas 75204
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Pfizer Investigational Site
Grand Rapids, Michigan 49506
?
mi
from
Grand Rapids, MI
Click here to add this to my saved trials
Pfizer Investigational Site
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Pfizer Investigational Site
Indianapolis, Indiana 46234
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Pfizer Investigational Site
Irvine, California 92606
?
mi
from
Irvine, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Jacksonville, Florida 32216
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Pfizer Investigational Site
La Jolla, California 92037
?
mi
from
La Jolla, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Las Vegas, Nevada 89128
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Pfizer Investigational Site
Lexington, Kentucky 40504
?
mi
from
Lexington, KY
Click here to add this to my saved trials
Pfizer Investigational Site
Los Angeles, California 90027
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Madison, Wisconsin 53713
?
mi
from
Madison, WI
Click here to add this to my saved trials
Pfizer Investigational Site
Martinez, California 94553
?
mi
from
Martinez, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Miami Beach, Florida 33139
?
mi
from
Miami Beach, FL
Click here to add this to my saved trials
Pfizer Investigational Site
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Pfizer Investigational Site
New Haven, Connecticut 06504
?
mi
from
New Haven, CT
Click here to add this to my saved trials
Pfizer Investigational Site
New York, New York 10029
?
mi
from
New York, NY
Click here to add this to my saved trials
Pfizer Investigational Site
Newport Beach, California 92663
?
mi
from
Newport Beach, CA
Click here to add this to my saved trials
Pfizer Investigational Site
North Charleston, South Carolina 29406
?
mi
from
North Charleston, SC
Click here to add this to my saved trials
Pfizer Investigational Site
Orange, California 92868
?
mi
from
Orange, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Palo Alto, California 94304
?
mi
from
Palo Alto, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Philadelphia, Pennsylvania 19134
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials
Pfizer Investigational Site
Phoenix, Arizona 85016
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Pfizer Investigational Site
Pittsburgh, Pennsylvania 15212
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
Pfizer Investigational Site
Portland, Oregon 97210
?
mi
from
Portland, OR
Click here to add this to my saved trials
Pfizer Investigational Site
Providence, Rhode Island 02905
?
mi
from
Providence, RI
Click here to add this to my saved trials
Pfizer Investigational Site
Rochester, New York 14642
?
mi
from
Rochester, NY
Click here to add this to my saved trials
Pfizer Investigational Site
Sacramento, California 95816
?
mi
from
Sacramento, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Saint Louis, Missouri 63139
?
mi
from
Saint Louis, MO
Click here to add this to my saved trials
Pfizer Investigational Site
Salt Lake City, Utah 84103
?
mi
from
Salt Lake City, UT
Click here to add this to my saved trials
Pfizer Investigational Site
San Diego, California 92123
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Pfizer Investigational Site
San Francisco, California 94115
?
mi
from
San Francisco, CA
Click here to add this to my saved trials
Pfizer Investigational Site
Seattle, Washington 98166
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Pfizer Investigational Site
Sun City, Arizona 85372
?
mi
from
Sun City, AZ
Click here to add this to my saved trials
Pfizer Investigational Site
Tampa, Florida 33609
?
mi
from
Tampa, FL
Click here to add this to my saved trials
Pfizer Investigational Site
Washington, District of Columbia 20003
?
mi
from
Washington,
Click here to add this to my saved trials