Capnography in the Post-Anesthesia Care Unit (PACU)
| Status: | Completed |
|---|---|
| Conditions: | Insomnia Sleep Studies, Cardiology, Pulmonary, Pulmonary |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 8/4/2018 |
| Start Date: | November 6, 2017 |
| End Date: | February 9, 2018 |
Preliminary Characterization of the Capnography Profile of Obstructive Sleep Apnea (OSA) Patients in the Post-Anesthesia Care Unit (PACU)
To understand if a progressive increase in end-tidal carbon dioxide (CO2) levels are
heralding respiratory difficulties before desaturation measured from capnography in
obstructive sleep apnea patients.
heralding respiratory difficulties before desaturation measured from capnography in
obstructive sleep apnea patients.
Background and Significance Carbon dioxide (CO2) levels can be monitored throughout the
respiratory cycle via capnography. In this way, capnography allows healthcare professionals
to follow a number of respiratory factors (i.e., depression, apnea, and hypercapnia) in
real-time. Earlier detection of alterations to ventilation status will better enable
providers to more accurately dose medications during procedures, especially in at-risk
patient populations such as patients with obstructive sleep apnea (OSA) [1, 2].
In a recent study of bariatric patients, approximately 15% experience postoperative pulmonary
complications. These patients could benefit significantly from capnography monitoring as this
measure can very accurately estimate the prevalence of respiratory complications.
Through this study we seek to understand how end-tidal CO2 (ETCO2) levels of patients with
obstructive sleep apnea vary when patients are in the post-anesthesia care unit (PACU). By
collecting information on patient outcomes, we hope to better understand the value of this
monitoring technique in an at-risk patient population. Though capnography in the PACU has not
previously been demonstrated to improve patient safety or satisfaction, capnography has never
been studied in a population of patients who are at risk of obstructive sleep apnea.
Study Design This is a prospective, blinded observational pilot study to monitor if changes
in end-tidal CO2 levels provide incremental value over pulse oximetry when detecting
respiratory difficulties (i.e., hypercapnia).
respiratory cycle via capnography. In this way, capnography allows healthcare professionals
to follow a number of respiratory factors (i.e., depression, apnea, and hypercapnia) in
real-time. Earlier detection of alterations to ventilation status will better enable
providers to more accurately dose medications during procedures, especially in at-risk
patient populations such as patients with obstructive sleep apnea (OSA) [1, 2].
In a recent study of bariatric patients, approximately 15% experience postoperative pulmonary
complications. These patients could benefit significantly from capnography monitoring as this
measure can very accurately estimate the prevalence of respiratory complications.
Through this study we seek to understand how end-tidal CO2 (ETCO2) levels of patients with
obstructive sleep apnea vary when patients are in the post-anesthesia care unit (PACU). By
collecting information on patient outcomes, we hope to better understand the value of this
monitoring technique in an at-risk patient population. Though capnography in the PACU has not
previously been demonstrated to improve patient safety or satisfaction, capnography has never
been studied in a population of patients who are at risk of obstructive sleep apnea.
Study Design This is a prospective, blinded observational pilot study to monitor if changes
in end-tidal CO2 levels provide incremental value over pulse oximetry when detecting
respiratory difficulties (i.e., hypercapnia).
Inclusion Criteria:
- > 18 years of age
- Patients who have are at TGH for bariatric surgery
- BMI > 30
- At risk of obstructive sleep apnea according to TGH STOP-BANG questionnaire
Exclusion Criteria:
- <18 years of age
- Not at risk of obstructive sleep apnea according to TGH STOP-BANG questionnaire
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