Whole-Neck Computed Tomography Perfusion Scan in Imaging Patients With Head and Neck Tumors
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 11/19/2017 |
| Start Date: | October 20, 2016 |
| End Date: | April 20, 2019 |
| Contact: | Bhushan Desai |
| Email: | bhushand@usc.edu |
| Phone: | 323-652-0343 |
A Pilot Study of Whole-Neck CT Perfusion With the Toshiba Aquilion ONE ViSION-320 Detector Row CT Scanner for Use in Head &Amp; Neck Tumor Patients
This pilot clinical trial studies how well whole-neck computed tomography perfusion scans
work in imaging patients with head and neck tumors. Diagnostic imaging procedures, such as
whole-neck computed tomography perfusions scans, may provide more information about the blood
supply to head and neck tumors which may help doctors plan better treatment.
work in imaging patients with head and neck tumors. Diagnostic imaging procedures, such as
whole-neck computed tomography perfusions scans, may provide more information about the blood
supply to head and neck tumors which may help doctors plan better treatment.
PRIMARY OBJECTIVES:
I. To assess the difference in whole-neck computed tomography perfusion (WNCTP) parameters
(blood volume [BV], blood flow [BF], capillary permeability [CP] and mean transit time [MTT])
between head and neck tumor masses (benign or malignant) and adjacent normal skeletal muscle
within the same patient.
II. To assess whether the difference in WNCTP parameters between tumor masses and adjacent
normal skeletal muscle is different between patients with benign tumor versus (vs.) malignant
tumor.
III. To assess the correlation in WNCTP parameters between tumor masses and adjacent normal
skeletal muscle.
IV. Determine if more suspicious cervical lymph nodes will be seen using the whole-neck
coverage employed in WNCTP compared to the limited coverage of traditional neck CTP.
OUTLINE:
Patients undergo WNCTP scan over 2-3 minutes during standard of care computed tomography
(CT).
After completion of study, patients are followed up within 2 days.
I. To assess the difference in whole-neck computed tomography perfusion (WNCTP) parameters
(blood volume [BV], blood flow [BF], capillary permeability [CP] and mean transit time [MTT])
between head and neck tumor masses (benign or malignant) and adjacent normal skeletal muscle
within the same patient.
II. To assess whether the difference in WNCTP parameters between tumor masses and adjacent
normal skeletal muscle is different between patients with benign tumor versus (vs.) malignant
tumor.
III. To assess the correlation in WNCTP parameters between tumor masses and adjacent normal
skeletal muscle.
IV. Determine if more suspicious cervical lymph nodes will be seen using the whole-neck
coverage employed in WNCTP compared to the limited coverage of traditional neck CTP.
OUTLINE:
Patients undergo WNCTP scan over 2-3 minutes during standard of care computed tomography
(CT).
After completion of study, patients are followed up within 2 days.
Inclusion Criteria:
- Confirmed or suspected head and neck tumor (benign or malignant)
- Scheduled for contrast CT (standard of care)
- No known allergies to contrast material
Exclusion Criteria:
- Known allergies to contrast material
- Pregnant or nursing
We found this trial at
1
site
1441 Eastlake Ave
Los Angeles, California 90033
Los Angeles, California 90033
(323) 865-3000
Principal Investigator: Mark Shiroishi
Phone: 323-865-9914
U.S.C./Norris Comprehensive Cancer Center The USC Norris Comprehensive Cancer Center, located in Los Angeles, is...
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