Chronic Cardiovascular Risk Outpatient Management in South Asians Using Digital Health Technology

The study will use telemedicine and the mobile health capabilities of smartphones to
facilitate communication of medical goals set by the treating physician to the subject in
between clinic visits, and to assess the daily medical and lifestyle change compliance of
enrolled Stanford subjects and provide virtual health coaching, as needed, to subjects to
achieve said goals. How patients comply with their specific medical and lifestyle goals all
affect their cardiovascular health, yet largely go unmeasured. These can now be measured with
a notification-based system in which subject-entered activity, medication compliance, and
dietary reporting data will be collected, assessed, and trigger appropriate responses by the
subject's Care Team, which includes their physician, nurse, dietitian, and assigned health
coach. We aim to collect this subject-reported activity and cardiovascular care plan
compliance data to provide much more quantitative data on type, duration, and intensity of
daily activities and compliance with the medication regimens of enrolled subjects.

The study will compare anthropometric cardiovascular risk biomarkers testing at the initial
visit and after 3 months, in subjects utilizing the HealthPals digital platform PLUS the
standard SSATHI clinic visits, versus subjects receiving only SSATHI clinic visits.

Inclusion Criteria:

- adult smartphone users

Exclusion Criteria:

- Subjects who do not own a smartphone or cannot access their mobile health data

- Patients unable to read English, as the initial version of the research app will be in
English

- Participants who are children (under 18 years old)

- Participants who are pregnant women

- Participants who are economically and educationally disadvantaged, decisionally
impaired, homeless people, or employees of Stanford University will be excluded due to
being of a vulnerable population.

- Participants who express active chest pain or shortness of breath in their first
clinic visit and are clinically deemed to require an emergency room evaluation will be
excluded

- Participants who have inability or unwillingness to use or connect to data services
for app messaging

- Participants with an upcoming surgical procedure (for instance, a clinic visit as part
of preoperative evaluation) that will significantly impair or block their ability to
follow the chronic disease management program during the study period

- Participants who have pre-existing participation in another clinical research
protocol.