Using a Novel Functional MRI Technique to Evaluate for Neurotoxicity
| Status: | Recruiting |
|---|---|
| Conditions: | Lymphoma |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 10/18/2018 |
| Start Date: | November 7, 2017 |
| End Date: | November 7, 2020 |
| Contact: | Behroze Vachha, MD, PhD |
| Email: | vachhab@mskcc.org |
| Phone: | 212-639-2706 |
Changes in Resting State Functional Connectivity in Patients With Central Nervous System Lymphoma Receiving High Dose Chemotherapy and Autologous Stem Cell Transplant
The purpose of this study is to test resting state functional Magnetic Resonance Imaging
(rsfMRI) scans to see if rsfMRI scans are better than the standard task based fMRI scans at
diagnosing or monitoring central nervous system lymphoma.
(rsfMRI) scans to see if rsfMRI scans are better than the standard task based fMRI scans at
diagnosing or monitoring central nervous system lymphoma.
Inclusion Criteria:
- Immunocompetent patients with newly diagnosed or recurrent non-Hodgkins lymphoma
involving the brain (primary or secondary), as demonstrated by MRI and histologic
confirmation either by positive CSF cytology for lymphoma or a monoclonal lymphocyte
population defined by cell surface markers, vitreous or uvea biopsy or brain biopsy
- Age 18-80 years
- Treatment plan for HDC-ASCT
- Fluent in English
- Patients who in the judgment of the investigators and/or consenting professional, are
able to understand the purpose of the study and provide informed consent will be
included.
Exclusion Criteria:
- Claustrophobia
- Any contraindication to the use of contrast and/or general guidelines for MR imaging
as per standard Department of Radiology imaging guidelines
- Unable to cooperate for MRI
We found this trial at
1
site
1275 York Ave
New York, New York 10021
New York, New York 10021
(212) 639-2000
Phone: 212-639-2706
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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