fMRI Connectivity in Fracture Hip Patients



Status:Recruiting
Conditions:Cognitive Studies, Hospital, Psychiatric
Therapuetic Areas:Psychiatry / Psychology, Other
Healthy:No
Age Range:65 - 99
Updated:1/9/2019
Start Date:January 29, 2017
End Date:November 2020
Contact:Judith M. Wishin, BSN
Email:jwishin@anest.ufl.edu
Phone:352-273-9096

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Trial Summary
Trial Overview
Inclusion Criteria

Functional Connectivity (With fMRI) as an Objective Measure of Postoperative Cognitive Function in Elderly Fracture Hip Patients

The long-term goal of this study is to evaluate cognitive function preoperatively and develop
techniques of intervention in the perioperative period which would optimize brain function
and functional recovery following surgery.

In this protocol, subjects who are anticipated to be operated for hip fracture will be
studied after surgery. Brief cognitive exam will be done followed by fMRI of connectivity and
diffusion tensor imaging (DTI). Connectivity (neuronal changes) and DTI (Anisotropy and mean
diffusivity) data will be compared with age matched controls and correlated with subjective
measures of cognition.

Inclusion Criteria:

- Patients 65 years and older

- Patients who have fracture hip and are anticipated to have surgery

Exclusion Criteria:

- Patients who have contraindications for MRI like pacemaker, automatic implanted
cardiac defibrillator (AICD), implanted infusion pumps etc.

- Patients who are claustrophobic

- Patients with severe cognitive impairment (who may not be able to cooperate during the
cognitive exam and fMRI)
We found this trial at
1
site
UF Health
Gainesville, Florida 32608
Phone: 352-273-9096
?
mi
from
Gainesville, FL
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