Effect of Hydroxycitrate on Urine Chemistry
| Status: | Recruiting |
|---|---|
| Conditions: | Nephrology, Nephrology |
| Therapuetic Areas: | Nephrology / Urology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/27/2019 |
| Start Date: | October 4, 2018 |
| End Date: | December 2019 |
| Contact: | David Goldfarb |
| Email: | david.goldfarb@nyumc.org |
| Phone: | 212 263 0744 |
Hydroxycitrate (HCA) is a compound extracted from the fruit, Garcinia Cambogia.
Hydroxycitrate supplements are available over the counter and are primarily promoted as a
weight loss supplement. There has been recent evidence that hydroxycitrate is a potent
inhibitor of calcium oxalate crystal growth and can lead to the dissolution of the crystals.
The purpose of this research study is to study the effect of Hydroxycitrate (HCA) supplements
on HCA urinary excretion and on urine chemistries in kidney stone formers and normal
subjects.
Hydroxycitrate supplements are available over the counter and are primarily promoted as a
weight loss supplement. There has been recent evidence that hydroxycitrate is a potent
inhibitor of calcium oxalate crystal growth and can lead to the dissolution of the crystals.
The purpose of this research study is to study the effect of Hydroxycitrate (HCA) supplements
on HCA urinary excretion and on urine chemistries in kidney stone formers and normal
subjects.
Inclusion Criteria:
Stone formers group:
- Established diagnosis of recurrent calcium stone formers
- Ages between 18 and 80
- Subjects must be able to read and follow instructions clearly and able to do 24 hour
urine collections.
- Subjects must be voluntarily willing and able to sign an informed consent form.
Control Group:
- In addition to b, c and d above, subjects must not have any known kidney disease or
family history of renal stones. Inclusion would be based on information provided by
participants.
Exclusion Criteria:
We found this trial at
1
site
550 1st Ave
New York, New York 10016
New York, New York 10016
(212) 263-7300
Principal Investigator: David Goldfarb, MD
Phone: 212-263-0744
New York University School of Medicine NYU School of Medicine has a proud history that...
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