Microarray Analysis of Gene Expression and Identification of Progenitor Cells in Lung Carcinoma
| Status: | Completed |
|---|---|
| Conditions: | Lung Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | February 2002 |
| End Date: | June 2011 |
| Contact: | Susan Jacobs, RN |
| Email: | ssjpulm@stanford.edu |
| Phone: | (650) 725-8082 |
This study will investigate gene expression profiles in normal human lung tissue, lung
carcinoma and metastatic tumor to the lung. The expression of up to 20,000 genes in a given
lung tissue sample will be examined by cDNA microarray analysis and compared to normal lung
tissue. In addition, we hope to identify a particular subset of lung cancer cells with an
enhanced capacity for proliferation and self-renewal , analogous to the stem cells recently
identified for certain types of leukemia, breast cancer and brain tumors.
carcinoma and metastatic tumor to the lung. The expression of up to 20,000 genes in a given
lung tissue sample will be examined by cDNA microarray analysis and compared to normal lung
tissue. In addition, we hope to identify a particular subset of lung cancer cells with an
enhanced capacity for proliferation and self-renewal , analogous to the stem cells recently
identified for certain types of leukemia, breast cancer and brain tumors.
Inclusion Criteria:Adults with non small cell lung cancer
Exclusion Criteria:NA
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