Effect of Acupuncture on Symptoms of Diarrhea and Pain in IBS
| Status: | Terminated |
|---|---|
| Conditions: | Irritable Bowel Syndrome (IBS), Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 90 |
| Updated: | 11/25/2017 |
| Start Date: | August 2001 |
| End Date: | January 2004 |
Effect of Acupuncture on Symptoms of Diarrhea and Pain in Diarrhea Predominant Irritable Bowel Syndrome (IBS) and Effect on Plasma Beta-endorphin and Serotonin Levels.
Acupuncture has been used for centuries in China in the treatment of diarrhea. Our hypothesis
is that acupuncture is effective in the treatment of abdominal pain and diarrhea in patients
with diarrhea-predominant IBS
is that acupuncture is effective in the treatment of abdominal pain and diarrhea in patients
with diarrhea-predominant IBS
Patients will complete a diary to determine if they qualify for the study. Patients will be
randomized to receive either acupuncture or sham acupuncture (needle insertion 1 cm away from
acupuncture site). Patients will be blinded to whether they are receiving acupuncture or sham
acupuncture. The acupuncturist is blinded as to the patient response. The patients will
undergo venupuncture to draw blood to determine sertotonin and beta-endorphin levels. They
will receive treatment in 12 sessions over 4 weeks. They will maintain a diary during this
time period to document level of pain and frequency of bowel movements. Blood will be drawn
at week 2 and 4 and, 6 weeks after cessation of treatment, subjects will again record
abdominal symptoms and frequency of bowel movements for 2 weeks. Blood will be drawn for
hormone levels at 8 weeks after completion of study.
randomized to receive either acupuncture or sham acupuncture (needle insertion 1 cm away from
acupuncture site). Patients will be blinded to whether they are receiving acupuncture or sham
acupuncture. The acupuncturist is blinded as to the patient response. The patients will
undergo venupuncture to draw blood to determine sertotonin and beta-endorphin levels. They
will receive treatment in 12 sessions over 4 weeks. They will maintain a diary during this
time period to document level of pain and frequency of bowel movements. Blood will be drawn
at week 2 and 4 and, 6 weeks after cessation of treatment, subjects will again record
abdominal symptoms and frequency of bowel movements for 2 weeks. Blood will be drawn for
hormone levels at 8 weeks after completion of study.
Inclusion Criteria:
- frequence of bowel movement of at least 3/day
- global disease severity of at least 3
Exclusion Criteria:
- taking medications which will influence frequency of bowel movement
- patient taking anticoagulants or suffering from coagulopathy
- pregancy
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