Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide



Status:Completed
Conditions:Diabetes, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:30 - 75
Updated:12/1/2017
Start Date:January 3, 2000
End Date:June 19, 2006

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-Blind Study to Compare the Durability of Glucose Lowering and Preservation of Pancreatic Beta-Cell Function of Rosiglitazone Monotherapy Compared to Metformin or Glyburide/Glibenclamide in Patients With Drug-Naive, Recently Diagnosed Type 2 Diabetes Mellitus

The study will compare and evaluate the effects of long-term treatment of monotherapy with
rosiglitazone, metformin and glyburide/glibenclamide on the improvement and maintenance of
glycemic control in patients with recently diagnosed type 2 diabetes mellitus.


Inclusion criteria:

- Newly diagnosed patients (< 3years) with type 2 diabetes.

- Fasting plasma glucose (FPG) range of 126-240 mg/dL at Screening.

- No previous treatment with oral or parenteral glucose-lowering therapy.

Exclusion criteria:

- History of lactic acidosis.

- Anemia (<11g for males, <10 g for females).

- Unstable or severe NY Heart Association-class 3 or 4.

- Any NY Heart Association congestive heart failure.

- Patients with chronic diseases requiring periodic or intermittent treatment with oral
or intravenous corticosteroids.
We found this trial at
136
sites
GSK Investigational Site
Albuquerque, New Mexico 87109
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
GSK Investigational Site
Albany, New York 12206
?
mi
from
Albany, NY
Click here to add this to my saved trials
GSK Investigational Site
Ann Arbor, Michigan 48109
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
GSK Investigational Site
Anniston, Alabama 36207
?
mi
from
Anniston, AL
Click here to add this to my saved trials
GSK Investigational Site
Arlington, Texas 76014
?
mi
from
Arlington, TX
Click here to add this to my saved trials
GSK Investigational Site
Atlanta, Georgia 30341
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
GSK Investigational Site
Austin, Texas 78705
?
mi
from
Austin, TX
Click here to add this to my saved trials
GSK Investigational Site
Baltimore, Maryland 21201
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
GSK Investigational Site
Bangor, Maine 04401
?
mi
from
Bangor, ME
Click here to add this to my saved trials
GSK Investigational Site
Beaumont, Texas 77701
?
mi
from
Beaumont, TX
Click here to add this to my saved trials
GSK Investigational Site
Bend, Oregon 97701
?
mi
from
Bend, OR
Click here to add this to my saved trials
GSK Investigational Site
Berkeley, California 94704
?
mi
from
Berkeley, CA
Click here to add this to my saved trials
GSK Investigational Site
Billings, Montana 59102
?
mi
from
Billings, MT
Click here to add this to my saved trials
GSK Investigational Site
Birmingham, Alabama 35249
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
GSK Investigational Site
Blue Ridge, Georgia 30513
?
mi
from
Blue Ridge, GA
Click here to add this to my saved trials
GSK Investigational Site
Boise, Idaho 83712
?
mi
from
Boise, ID
Click here to add this to my saved trials
GSK Investigational Site
Boston, Massachusetts 02115
?
mi
from
Boston, MA
Click here to add this to my saved trials
GSK Investigational Site
Boulder, Colorado 80304
?
mi
from
Boulder, CO
Click here to add this to my saved trials
GSK Investigational Site
Bristol, Tennessee 37620
?
mi
from
Bristol, TN
Click here to add this to my saved trials
GSK Investigational Site
Bronx, New York 10461
?
mi
from
Bronx, NY
Click here to add this to my saved trials
GSK Investigational Site
Charleston, South Carolina 29425
?
mi
from
Charleston, SC
Click here to add this to my saved trials
GSK Investigational Site
Charleston, West Virginia 25304
?
mi
from
Charleston, WV
Click here to add this to my saved trials
GSK Investigational Site
Charlottesville, Virginia 22903
?
mi
from
Charlottesville, VA
Click here to add this to my saved trials
GSK Investigational Site
Cherry Hill, New Jersey 08003
?
mi
from
Cherry Hill, NJ
Click here to add this to my saved trials
GSK Investigational Site
Chicago, Illinois 60611
?
mi
from
Chicago, IL
Click here to add this to my saved trials
GSK Investigational Site
Cincinnati, Ohio 45229
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
GSK Investigational Site
Cleveland, Ohio 44195
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
GSK Investigational Site
Columbia, South Carolina 29203
?
mi
from
Columbia, SC
Click here to add this to my saved trials
GSK Investigational Site
Corona, California 92882
?
mi
from
Corona, CA
Click here to add this to my saved trials
GSK Investigational Site
Corpus Christi, Texas 78405
?
mi
from
Corpus Christi, TX
Click here to add this to my saved trials
GSK Investigational Site
Dallas, Texas 75230
?
mi
from
Dallas, TX
Click here to add this to my saved trials
GSK Investigational Site
Denver, Colorado 80206
?
mi
from
Denver, CO
Click here to add this to my saved trials
GSK Investigational Site
Detroit, Michigan 48202
?
mi
from
Detroit, MI
Click here to add this to my saved trials
GSK Investigational Site
Downingtown, Pennsylvania 19335
?
mi
from
Downingtown, PA
Click here to add this to my saved trials
GSK Investigational Site
Dunwoody, Georgia 30338
?
mi
from
Dunwoody, GA
Click here to add this to my saved trials
GSK Investigational Site
Durham, North Carolina 27705
?
mi
from
Durham, NC
Click here to add this to my saved trials
GSK Investigational Site
Endwell, New York 13760
?
mi
from
Endwell, NY
Click here to add this to my saved trials
GSK Investigational Site
Englewood, Colorado 80110
?
mi
from
Englewood, CO
Click here to add this to my saved trials
GSK Investigational Site
Eugene, Oregon 97401
?
mi
from
Eugene, OR
Click here to add this to my saved trials
GSK Investigational Site
Evansville, Indiana 47714
?
mi
from
Evansville, IN
Click here to add this to my saved trials
GSK Investigational Site
Fair Oaks, California 95628
?
mi
from
Fair Oaks, CA
Click here to add this to my saved trials
GSK Investigational Site
Fayetteville, Georgia 30214
?
mi
from
Fayetteville, GA
Click here to add this to my saved trials
GSK Investigational Site
Feasterville, Pennsylvania 19053
?
mi
from
Feasterville, PA
Click here to add this to my saved trials
GSK Investigational Site
Federal Way, Washington 98003
?
mi
from
Federal Way, WA
Click here to add this to my saved trials
GSK Investigational Site
Fleetwood, Pennsylvania 19522
?
mi
from
Fleetwood, PA
Click here to add this to my saved trials
GSK Investigational Site
Flushing, New York 11355
?
mi
from
Flushing, NY
Click here to add this to my saved trials
GSK Investigational Site
Fort Myers, Florida 33916
?
mi
from
Fort Myers, FL
Click here to add this to my saved trials
GSK Investigational Site
Fort Worth, Texas 76104
?
mi
from
Fort Worth, TX
Click here to add this to my saved trials
GSK Investigational Site
Fremont, California 94538
?
mi
from
Fremont, CA
Click here to add this to my saved trials
GSK Investigational Site
Fresno, California 93720
?
mi
from
Fresno, CA
Click here to add this to my saved trials
GSK Investigational Site
Fullerton, California 92835
?
mi
from
Fullerton, CA
Click here to add this to my saved trials
GSK Investigational Site
Greenbrae, California 94904
?
mi
from
Greenbrae, CA
Click here to add this to my saved trials
GSK Investigational Site
Greer, South Carolina 29651
?
mi
from
Greer, SC
Click here to add this to my saved trials
GSK Investigational Site
Gurnee, Illinois 60031
?
mi
from
Gurnee, IL
Click here to add this to my saved trials
GSK Investigational Site
Harbor City, California 90710
?
mi
from
Harbor City, CA
Click here to add this to my saved trials
GSK Investigational Site
Healdsburg, California 95448
?
mi
from
Healdsburg, CA
Click here to add this to my saved trials
GSK Investigational Site
Henderson, Nevada 89052
?
mi
from
Henderson, NV
Click here to add this to my saved trials
GSK Investigational Site
Hermitage, Pennsylvania 16148
?
mi
from
Hermitage, PA
Click here to add this to my saved trials
GSK Investigational Site
Hershey, Pennsylvania 17033
?
mi
from
Hershey, PA
Click here to add this to my saved trials
GSK Investigational Site
Hollywood, Florida 33021
?
mi
from
Hollywood, FL
Click here to add this to my saved trials
GSK Investigational Site
Honolulu, Hawaii 96813
?
mi
from
Honolulu, HI
Click here to add this to my saved trials
GSK Investigational Site
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
GSK Investigational Site
Huntington, West Virginia 25701
?
mi
from
Huntington, WV
Click here to add this to my saved trials
GSK Investigational Site
Indianapolis, Indiana 46202
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
GSK Investigational Site
Irving, Texas 75039
?
mi
from
Irving, TX
Click here to add this to my saved trials
GSK Investigational Site
Jackson, Mississippi 39202
?
mi
from
Jackson, MS
Click here to add this to my saved trials
GSK Investigational Site
Jacksonville, Florida 32207
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
GSK Investigational Site
Jefferson Hills, Pennsylvania 15025
?
mi
from
Jefferson Hills, PA
Click here to add this to my saved trials
GSK Investigational Site
Kansas City, Missouri 64128
?
mi
from
Kansas City, MO
Click here to add this to my saved trials
GSK Investigational Site
La Jolla, California 92093
?
mi
from
La Jolla, CA
Click here to add this to my saved trials
GSK Investigational Site
Lake Charles, Louisiana 70601
?
mi
from
Lake Charles, LA
Click here to add this to my saved trials
GSK Investigational Site
Lansing, Michigan 48917
?
mi
from
Lansing, MI
Click here to add this to my saved trials
GSK Investigational Site
Lexington, Kentucky 40504
?
mi
from
Lexington, KY
Click here to add this to my saved trials
GSK Investigational Site
Little Rock, Arkansas 72205
?
mi
from
Little Rock, AR
Click here to add this to my saved trials
GSK Investigational Site
Loma Linda, California 92357
?
mi
from
Loma Linda, CA
Click here to add this to my saved trials
GSK Investigational Site
Longmont, Colorado 80501
?
mi
from
Longmont, CO
Click here to add this to my saved trials
GSK Investigational Site
Los Angeles, California 90025
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
GSK Investigational Site
Madison, Wisconsin 53792
?
mi
from
Madison, WI
Click here to add this to my saved trials
GSK Investigational Site
Melbourne, Florida 32935
?
mi
from
Melbourne, FL
Click here to add this to my saved trials
GSK Investigational Site
Mesa, Arizona 85206
?
mi
from
Mesa, AZ
Click here to add this to my saved trials
GSK Investigational Site
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
GSK Investigational Site
Midland, Texas 79701
?
mi
from
Midland, TX
Click here to add this to my saved trials
GSK Investigational Site
Milwaukee, Wisconsin 53215
?
mi
from
Milwaukee, WI
Click here to add this to my saved trials
GSK Investigational Site
Minneapolis, Minnesota 55404
?
mi
from
Minneapolis, MN
Click here to add this to my saved trials
GSK Investigational Site
Modesto, California 95350
?
mi
from
Modesto, CA
Click here to add this to my saved trials
GSK Investigational Site
Mogadore, Ohio 44260
?
mi
from
Mogadore, OH
Click here to add this to my saved trials
GSK Investigational Site
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
GSK Investigational Site
New Orleans, Louisiana 70112
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
GSK Investigational Site
New York, New York 10032
?
mi
from
New York, NY
Click here to add this to my saved trials
GSK Investigational Site
Newport News, Virginia 23606
?
mi
from
Newport News, VA
Click here to add this to my saved trials
GSK Investigational Site
Ogden, Utah 84403
?
mi
from
Ogden, UT
Click here to add this to my saved trials
GSK Investigational Site
Oklahoma City, Oklahoma 73112
?
mi
from
Oklahoma City, OK
Click here to add this to my saved trials
GSK Investigational Site
Olive Branch, Mississippi 38654
?
mi
from
Olive Branch, MS
Click here to add this to my saved trials
GSK Investigational Site
Omaha, Nebraska 68131
?
mi
from
Omaha, NE
Click here to add this to my saved trials
GSK Investigational Site
Oregon, Wisconsin 53575
?
mi
from
Oregon, WI
Click here to add this to my saved trials
GSK Investigational Site
Orlando, Florida 32806
?
mi
from
Orlando, FL
Click here to add this to my saved trials
GSK Investigational Site
Palm Harbor, Florida 34684
?
mi
from
Palm Harbor, FL
Click here to add this to my saved trials
GSK Investigational Site
Pasadena, California 91105
?
mi
from
Pasadena, CA
Click here to add this to my saved trials
GSK Investigational Site
Philadelphia, Pennsylvania 19104
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials
GSK Investigational Site
Pittsburgh, Pennsylvania 15213
?
mi
from
Pittsburgh, PA
Click here to add this to my saved trials
GSK Investigational Site
Portland, Oregon 97227
?
mi
from
Portland, OR
Click here to add this to my saved trials