Utility of Real-Time Contrast Enhanced Ultrasound (CEUS) in the Evaluation of Soft Tissue Hematomas
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/27/2019 |
| Start Date: | February 27, 2018 |
| End Date: | December 2019 |
Traumatic and non-traumatic soft tissue hematomas are frequently encountered in the acute
care setting. The incidence of these hematomas appears to be on the rise secondary to the
increased use of anticoagulants among older patients for a variety of medical conditions.
The management of soft tissue hematomas depends on the accurate diagnosis of any ongoing
bleeding as well as of identification of the injured vessel type. While the majority of cases
can be managed conservatively, expanding hematomas leading to hemodynamic instability or
ongoing blood loss might require embolization or surgical intervention. The mainstay
diagnostic imaging modality is multidetector computed tomography (MDCT) with intravenous
contrast that allows accurate assessment of hematoma size, location as well as evaluation for
active extravasation. However, many patients cannot undergo CT imaging due to underlying
kidney disease, allergy to contrast, or due to concerns for radiation exposure, especially in
young age. Currently there are no alternative tests for these patients with a similarly high
diagnostic accuracy available.
This study intends to establish an imaging protocol and investigate the utility of
contrast-enhanced ultrasound (CEUS) in the diagnostic work-up of soft tissue hematoma as an
ionizing radiation-free alternative to computed tomography (CT) that can be used independent
from the kidney function of the patient.
care setting. The incidence of these hematomas appears to be on the rise secondary to the
increased use of anticoagulants among older patients for a variety of medical conditions.
The management of soft tissue hematomas depends on the accurate diagnosis of any ongoing
bleeding as well as of identification of the injured vessel type. While the majority of cases
can be managed conservatively, expanding hematomas leading to hemodynamic instability or
ongoing blood loss might require embolization or surgical intervention. The mainstay
diagnostic imaging modality is multidetector computed tomography (MDCT) with intravenous
contrast that allows accurate assessment of hematoma size, location as well as evaluation for
active extravasation. However, many patients cannot undergo CT imaging due to underlying
kidney disease, allergy to contrast, or due to concerns for radiation exposure, especially in
young age. Currently there are no alternative tests for these patients with a similarly high
diagnostic accuracy available.
This study intends to establish an imaging protocol and investigate the utility of
contrast-enhanced ultrasound (CEUS) in the diagnostic work-up of soft tissue hematoma as an
ionizing radiation-free alternative to computed tomography (CT) that can be used independent
from the kidney function of the patient.
Inclusion Criteria:
- Adult patients over the age of 18 who have a clinical suspicion of an actively
bleeding soft-tissue hematoma as determined by the treating emergency provider.
Enrollment will be for one year or until a target of 20 patients is enrolled.
Exclusion Criteria:
- The investigators will exclude persons under the age of eighteen, vulnerable
populations (pregnant patients and prisoners), need for immediate procedural
intervention and those with known hypersensitivity to sulfur hexafluoride lipid
containing microspheres as well as those who have a soft-tissue hematomas that are in
an unfavorable anatomical location for ultrasound imaging.
We found this trial at
1
site
200 First Street SW
Rochester, Minnesota 55905
Rochester, Minnesota 55905
507-284-2511
Phone: 507-255-4732
Mayo Clinic Rochester Mayo Clinic is a nonprofit worldwide leader in medical care, research and...
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