Components of Social Functioning in Survivors of Pediatric Brain Tumors
| Status: | Recruiting |
|---|---|
| Conditions: | Brain Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 8 - 12 |
| Updated: | 1/20/2019 |
| Start Date: | January 30, 2018 |
| End Date: | February 2021 |
| Contact: | Victoria W. Willard, PhD |
| Email: | referralinfo@stjude.org |
| Phone: | 866-278-5833 |
Children with brain tumors are at risk for a number of psychological late effects, including
neurocognitive and social deficits. This observational study focuses on assessment of social
functioning, including social-cognitive and neurocognitive abilities, in survivors of
pediatric brain tumors. This study will also assess the influence of medical factors,
including diagnosis and age at diagnosis, on social functioning.
PRIMARY OBJECTIVE: Examine the impact of social-cognitive and neurocognitive abilities on
social functioning in survivors of pediatric brain tumors.
SECONDARY OBJECTIVE: Assess the influence of medical factors such as diagnosis and age at
diagnosis on the social functioning of survivors of pediatric brain tumors.
neurocognitive and social deficits. This observational study focuses on assessment of social
functioning, including social-cognitive and neurocognitive abilities, in survivors of
pediatric brain tumors. This study will also assess the influence of medical factors,
including diagnosis and age at diagnosis, on social functioning.
PRIMARY OBJECTIVE: Examine the impact of social-cognitive and neurocognitive abilities on
social functioning in survivors of pediatric brain tumors.
SECONDARY OBJECTIVE: Assess the influence of medical factors such as diagnosis and age at
diagnosis on the social functioning of survivors of pediatric brain tumors.
Assessment of social and neurocognitive functioning in survivors of pediatric brain tumors
who are least two years post-therapy and between 8 and 12 years of age will be included.
Participants will be recruited from two tumor types: 1) medulloblastoma, and 2) other brain
tumors that were not treated with craniospinal irradiation. Upon enrollment, participants
will complete standard psychological questionnaires used to evaluate both performance-based
and self-report measures of social and neurocognitive functioning. Parents will complete
questionnaires. Families will be asked for permission to contact teachers to complete
additional questionnaires. Children will identify their best friend as part of their
questionnaires and will be asked permission to contact this friend to complete two
questionnaires. Finally, children will be asked to complete an online daily diary of social
interactions for seven days.
who are least two years post-therapy and between 8 and 12 years of age will be included.
Participants will be recruited from two tumor types: 1) medulloblastoma, and 2) other brain
tumors that were not treated with craniospinal irradiation. Upon enrollment, participants
will complete standard psychological questionnaires used to evaluate both performance-based
and self-report measures of social and neurocognitive functioning. Parents will complete
questionnaires. Families will be asked for permission to contact teachers to complete
additional questionnaires. Children will identify their best friend as part of their
questionnaires and will be asked permission to contact this friend to complete two
questionnaires. Finally, children will be asked to complete an online daily diary of social
interactions for seven days.
Inclusion Criteria:
- Diagnosis of medulloblastoma or other brain tumor
- Current age between 8 and 12 years, inclusive
- At least 2 years post-completion of therapy
- Enrolled in school full-time
- English speaking
- Cognitive and language capacity to complete measures
- Teacher inclusion: Consent received from survivor and parent to contact.
- Best Friends inclusion: (1) Consent received from survivor and parent to contact, (2)
English-speaking, (3) Cognitive capacity to complete questionnaires as judged by the
parent during the consent process.
Exclusion Criteria:
- Diagnosis of a genetic disorder/pre-existing neurodevelopmental condition associated
with neurocognitive or social impairment (e.g., autism, Neurofibromatosis Type 1
(NF1), Down syndrome
- Homeschooled or full-time special education
- IQ less than 70 as documented in the medical record
- Inability or unwillingness of research participant or legal guardian/representative to
give written informed consent.
- Other tumor cohort exclusion: (1) diagnosis of craniopharyngioma, (2) treatment
history includes craniospinal irradiation (CSI).
We found this trial at
1
site
262 Danny Thomas Pl
Memphis, Tennessee 38105
Memphis, Tennessee 38105
(901) 495-3300
Principal Investigator: Victoria W. Willard, PhD
Phone: 866-278-5833
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