Treating Oxidative Stress and the Metabolic Pathology of Autism
| Status: | Suspended |
|---|---|
| Conditions: | Neurology, Psychiatric |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 3 - 7 |
| Updated: | 4/21/2016 |
| Start Date: | June 2008 |
| End Date: | February 2017 |
Hypothesis: Many children with autism have impaired methylation and
antioxidant/detoxification capacity and chronic oxidative stress. A targeted nutritional
intervention that is designed to correct the metabolic imbalance will normalize their
metabolic profile and improve measures of autistic behavior.
antioxidant/detoxification capacity and chronic oxidative stress. A targeted nutritional
intervention that is designed to correct the metabolic imbalance will normalize their
metabolic profile and improve measures of autistic behavior.
Inclusion Criteria:
- ADOS and DSM-IV (299.0) diagnosis of Autistic Disorder
- Both sexes
- Age range 3-7
Exclusion Criteria:
- Pervasive Developmental Disorder, Not Otherwise Specified (PDD-NOS)
- Asperger's
- Rett syndrome
- Fragile X
- Tuberous sclerosis or other genetic conditions associated with autism
- Frequent seizures
- Recurrent or current infection
- Severe gastrointestinal distress
- Recent supplement use
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