DASH-Sodium Trial in Adolescents



Status:Terminated
Conditions:High Blood Pressure (Hypertension)
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:11 - 15
Updated:12/10/2017
Start Date:October 2016
End Date:October 18, 2017

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The Camp DASH study trial will compare the effect of two dietary patterns and two levels of
sodium intake on blood pressure and blood lipids in adolescents in the upper third of
distribution for blood pressure. The two dietary patterns are based on the Dietary Approaches
to Stop Hypertension (DASH) trial in adults.

The Camp DASH study is a controlled trial. the aim of which is to compare the effect of two
dietary patterns and two levels of sodium intake on blood pressure and blood lipids in
adolescents in the upper third of distribution for blood pressure. The study also assesses
whether influences on blood pressure and blood lipids of dietary interventions vary according
to sex, race/ethnic groups, baseline levels, and other personal characteristics. The proposed
dietary interventions of DASH dietary patterns and sodium reduction have been shown to be
effective in lowering blood pressure in adults. The two dietary patterns are based on the
Dietary Approaches to Stop Hypertension (DASH) trial in adults. They are a Usual diet typical
of what many American adolescents eat, and a DASH‐type diet. The DASH diet is rich in fruits,
vegetables, and low‐fat dairy foods and low in saturated fat and total fat compared to the
Usual diet. The two sodium levels are High reflecting current US consumption and Low
reflecting current recommended intake levels. Weight will be held constant by adjusting
energy intake. The study participants will live in a residence hall on the Purdue campus
where all food and beverages will be provided, and meals and snacks will be supervised.

Inclusion Criteria:

- White, black, Hispanic, and Asian

- SBP in the upper one‐third of the distribution for their given sex, age, and height

Exclusion Criteria:

- Pre‐existing lipid disorders, abnormal liver or kidney function

- Taking medications that alter mineral absorption or metabolism, affect blood pressure
or lipids

- If subjects are taking dietary supplements and refuse to discontinue them 2 months
prior to the study.

- Taking non‐prescription illegal drugs, smoke, or drink alcohol

- Pregnancy

- Carry an epi pen for food-related allergies
We found this trial at
2
sites
705 Riley Hospital Drive
Indianapolis, Indiana 46202
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Indianapolis, IN
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West Lafayette, IN
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