Ideal Time of Oxytocin Infusion During Cesarean Section



Status:Recruiting
Conditions:Hospital, Women's Studies, Women's Studies
Therapuetic Areas:Other, Reproductive
Healthy:No
Age Range:18 - Any
Updated:8/9/2018
Start Date:September 13, 2017
End Date:July 2020
Contact:Whitney Dunn, MD
Email:whitney.dunn@lumc.edu
Phone:708-216-4033

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This study will evaluate if the timing of oxytocin administration in cesarean deliveries will
affect the amount of maternal blood loss. Half of participants will receive oxytocin after
delivery of the fetal anterior shoulder and the other half will receive oxytocin after
delivery of the placenta. We hypothesize that administering oxytocin after delivery of the
shoulder, will result in less overall maternal blood loss.

Oxytocin is a routinely administered medication for both vaginal and cesarean deliveries in
the third stage of labor, as part of standard of care in the United States. This medication
helps to reduce overall blood loss, by functioning as a uterotonic. Currently evidence is
lacking to direct timing of oxytocin administration in cesarean deliveries.

This study will evaluate both estimated and quantitative blood loss for both groups of
patients. It will also compare the change from pre-operative to post-operative hemoglobin
levels.

Inclusion Criteria:

- Women undergoing cesarean section at Loyola Hospital

- Women who read and speak the English and/or Spanish language

- Women age 18 or older

Exclusion Criteria:

- Women who deliver vaginally

- Gestation under 37 weeks and 0 days

- Women with coagulopathies

- Multiple gestation pregnancies

- Antepartum hemorrhage for example abruption

- Placental abnormalities for example previa, accreta
We found this trial at
1
site
2160 South 1st Avenue
Maywood, Illinois 60153
(888) 584-7888
Phone: 708-216-4033
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