Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer
Status: | Recruiting |
---|---|
Conditions: | Prostate Cancer |
Therapuetic Areas: | Oncology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 3/16/2019 |
Start Date: | November 16, 2017 |
End Date: | December 2030 |
Phase III IGRT and SBRT vs IGRT and Hypofractionated IMRT for Localized Intermediate Risk Prostate Cancer
This randomized phase III trial studies how well stereotactic body radiation therapy works
compared to intensity-modulated radiation therapy in treating patients with stage IIA-B
prostate cancer. Radiation therapy uses high energy x-rays to kill tumor cells and shrink
tumors. Stereotactic body radiation therapy is a specialized radiation therapy that sends
x-rays directly to the tumor using smaller doses over several days and may cause less damage
to normal tissue. Stereotactic body radiation therapy may work better in treating patients
with prostate cancer.
compared to intensity-modulated radiation therapy in treating patients with stage IIA-B
prostate cancer. Radiation therapy uses high energy x-rays to kill tumor cells and shrink
tumors. Stereotactic body radiation therapy is a specialized radiation therapy that sends
x-rays directly to the tumor using smaller doses over several days and may cause less damage
to normal tissue. Stereotactic body radiation therapy may work better in treating patients
with prostate cancer.
PRIMARY OBJECTIVES:
I. To determine whether stereotactic body radiation therapy (SBRT) can be shown to be
superior to hypofractionated intensity-modulated radiation therapy (IMRT) in terms of
genitourinary (GU) and gastrointestinal (GI) toxicity by having fewer patients that
experience a minimal important decline (MID) in urinary irritation/obstructive and bowel
Health Related Quality of Life (HRQOL) as measured by Expanded Prostate Cancer Index
Composite (EPIC)-26 at 24 months post completion of therapy.
SECONDARY OBJECTIVES:
I. To determine if SBRT (5 fractions of 7.25 Gy) is superior to hypofractionated IMRT (28
fractions of 2.5 Gy) as measured by disease free survival (DFS).
II. To determine whether SBRT can be shown to be superior to hypofractionated IMRT at 12 and
24 months post completion of therapy in terms of HRQOL by having fewer patients that
experience a minimal important decline (MID) bowel (12 months only) sexual, hormonal, urinary
irritation/obstructive (12 months only) and in urinary incontinence HRQOL as measured by
EPIC-26.
III. To determine if SBRT (5 fractions of 7.25 Gy) is superior to hypofractionated IMRT (28
fractions of 2.5 Gy) as measured by biochemical failure, overall survival, local failure,
prostate cancer specific survival, and distant metastases.
IV. To determine if prostate imaging-reporting and data system (PIRADS)version (v)2 = 4/5
disease is predictive for biochemical failure.
TERTIARY OBJECTIVES:
I. To determine whether a potentially more expensive therapy, SBRT, would be cost-effective
than standard hypofractionated IMRT as measured by the European Quality of Life Five
Dimension Five Level Scale Questionnaire (EQ-5D-5L).
II. To determine if disease characteristics captured on MRI can be used to predict which
patients will respond to SBRT versus hypofractionated IMRT.
III. Collect specimens for future translational research analyses.
OUTLINE: Patients are randomized into 1 of 2 arms.
ARM I: Patients undergo IMRT once daily for 5 fractions per week for 28 fractions over less
than 32 business days.
ARM II: Patients undergo SBRT at least every other day for 2-3 fractions per week for 5
fractions over less than 12 business days.
After completion of study treatment, patients are followed up every 6-12 months until death
or study termination.
I. To determine whether stereotactic body radiation therapy (SBRT) can be shown to be
superior to hypofractionated intensity-modulated radiation therapy (IMRT) in terms of
genitourinary (GU) and gastrointestinal (GI) toxicity by having fewer patients that
experience a minimal important decline (MID) in urinary irritation/obstructive and bowel
Health Related Quality of Life (HRQOL) as measured by Expanded Prostate Cancer Index
Composite (EPIC)-26 at 24 months post completion of therapy.
SECONDARY OBJECTIVES:
I. To determine if SBRT (5 fractions of 7.25 Gy) is superior to hypofractionated IMRT (28
fractions of 2.5 Gy) as measured by disease free survival (DFS).
II. To determine whether SBRT can be shown to be superior to hypofractionated IMRT at 12 and
24 months post completion of therapy in terms of HRQOL by having fewer patients that
experience a minimal important decline (MID) bowel (12 months only) sexual, hormonal, urinary
irritation/obstructive (12 months only) and in urinary incontinence HRQOL as measured by
EPIC-26.
III. To determine if SBRT (5 fractions of 7.25 Gy) is superior to hypofractionated IMRT (28
fractions of 2.5 Gy) as measured by biochemical failure, overall survival, local failure,
prostate cancer specific survival, and distant metastases.
IV. To determine if prostate imaging-reporting and data system (PIRADS)version (v)2 = 4/5
disease is predictive for biochemical failure.
TERTIARY OBJECTIVES:
I. To determine whether a potentially more expensive therapy, SBRT, would be cost-effective
than standard hypofractionated IMRT as measured by the European Quality of Life Five
Dimension Five Level Scale Questionnaire (EQ-5D-5L).
II. To determine if disease characteristics captured on MRI can be used to predict which
patients will respond to SBRT versus hypofractionated IMRT.
III. Collect specimens for future translational research analyses.
OUTLINE: Patients are randomized into 1 of 2 arms.
ARM I: Patients undergo IMRT once daily for 5 fractions per week for 28 fractions over less
than 32 business days.
ARM II: Patients undergo SBRT at least every other day for 2-3 fractions per week for 5
fractions over less than 12 business days.
After completion of study treatment, patients are followed up every 6-12 months until death
or study termination.
Inclusion Criteria:
- Previously untreated (no local therapy such as surgery, radiation cryotherapy, HIFU,
etc.) localized adenocarcinoma of the prostate with the following clinical findings:
- Clinical stage by digital rectal exam of either T1c or T2a/b (limited to one side
of the gland); (American Joint Committee on Cancer [AJCC], version 7) or cT1a-c
or 2a or 2b,
- Stages T1a-T1b are eligible if patient underwent transurethral prostatic
resection (TURP), the patient must meet one of the following 3 criteria: 1)
Gleason score must be Gleason 7(3+4) with a PSA < 20 ng/mL, or 2) Gleason 6(3+3)
with a PSA > 10 ng/mL and < 20 ng/mL; (AJCC, version 7) or 3) Group Grade 1 or 2
- If patient is receiving a 5-alpha reductase inhibitor at the time of
enrollment the baseline PSA value may be double the initial value and the
medication should be discontinued but a washout period is not required to
eligible, a PSA drawn while still on the medicine must be:
- < 10 ng/mL if Gleason 7(3+4) (Note: This patient would be on
stratification level 1 if PSA < 5 ng/mL and stratification level 2 if
less than 10 ng/mL).
- > 5 ng/mL and less than 10 ng/mL for Gleason 6(3+3) (Note: This
patients would be on stratification level 3).
- Percent of submitted positive core biopsies must be < 50% of all sextants
(Sextant refers to the bilateral base, mid and apex of the gland and the left and
right, resulting in six sections or sextants. Biopsies may take 2 from each
sextant. If more than 12 are sampled, some may be from a targeted region possibly
with multiple cores to ensure adequate tissue.)
- NOTE: all cores from a targeted lesion will be counted as an N of 1 core for
calculating percent positive cores in total
- The prostate volume must be < 60 cc as reported at time of biopsy or by separate
measure with ultrasound or other imaging modalities including magnetic resonance
imaging (MRI) or computed tomography (CT) scan
- Patients in active surveillance who elect to be treated are eligible if they meet
protocol requirements
- History and physical including a digital rectal exam 60 days prior to registration
- Eastern Cooperative Oncology Group (ECOG) performance status 0-1 60 days prior to
registration
- MRI of pelvis (compliant with PIRADSv2 guidelines) within 90 days prior to
registration
- Bone scan or sodium fluoride positron emission tomography (PET) scan within 90 days
prior to registration
- Charlson modified co-morbidity score =< 3 for patients under 60 and =< 4 for patients
60 and over 21 days prior to registration
- International prostate symptom score (IPSS) of < 15 21 days prior to registration
- The patient must provide study-specific informed consent prior to study entry
- Willingness and ability to complete the Expanded Prostate Cancer Index Composite
(EPIC-26) questionnaire
- Completion of all items of the EPIC-26 which will be data entered at registration 60
days prior to registration
- Only English, Spanish, and French-speaking patients are eligible to participate
Exclusion Criteria:
- Definitive clinical or radiologic evidence of metastatic disease; no nodal involvement
or evidence of metastatic disease allowed as defined by screening of the pelvis and a
bone scan or sodium fluoride PET scan
- Definitive T3 disease on MRI
- Prior or current invasive malignancy with current evidence of active disease within
the past 3 years
- Prior systemic chemotherapy for the study cancer; note that prior chemotherapy for a
different cancer is allowable; must be off treatment for at least 3 years; [applicable
only to studies that incorporate systemic therapy]
- Prior radiotherapy to the region of the study cancer that would result in overlap of
radiation therapy fields
- The use of hormonal therapy is not allowed; if the patient in on a 5-alpha reductase
inhibitor, then they should be stopped prior to treatment once enrolled onto the
study; no washout period is required for this study to participate
- Severe, active co-morbidity defined as follows:
- Human immunodeficiency virus (HIV) positive with CD4 count < 200
cells/microliter; Note that patients who are HIV positive are eligible, provided
they are under treatment with highly active antiretroviral therapy (HAART) and
have a CD4 count >= 200 cells/microliter within 30 days prior to registration;
Note also that HIV testing is not required for eligibility for this protocol
- Hepatic insufficiency resulting in clinical jaundice and/or coagulation defects;
note, however, that laboratory tests for liver function and coagulation
parameters are not required for entry into this protocol; (patients on Coumadin
or other blood thinning agents are eligible for this study)
- Contraindication to MRI
- Cardiac pacemaker or defibrillator
- Surgically implanted electrical devices such as spinal stimulation devices or
intracranial stimulation devices, cochlear implants, the presence of metallic
foreign bodies in the orbits, and incompatible old mechanical heart valves and
aneurysm clips
We found this trial at
148
sites
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Principal Investigator: Jeff M. Michalski
Phone: 800-600-3606
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
Click here to add this to my saved trials
1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
Albuquerque, New Mexico 87131
(505) 272-4946
Principal Investigator: Thomas M. Schroeder
Phone: 505-925-0366
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
Click here to add this to my saved trials
529 West Markham Street
Little Rock, Arkansas 72205
Little Rock, Arkansas 72205
(501) 686-7000
Principal Investigator: Sanjay Maraboyina
Phone: 501-686-8274
University of Arkansas for Medical Sciences The University of Arkansas for Medical Sciences (UAMS) in...
Click here to add this to my saved trials
Abilene, Texas 79606
Principal Investigator: Vivek S. Kavadi
Phone: 412-339-5294
Click here to add this to my saved trials
1 Akron General Avenue
Akron, Ohio 44307
Akron, Ohio 44307
Principal Investigator: Mitchel L. Fromm
Phone: 866-223-8100
Click here to add this to my saved trials
4650 Jefferson Lane Northeast
Albuquerque, New Mexico 87109
Albuquerque, New Mexico 87109
Principal Investigator: Thomas M. Schroeder
Phone: 505-272-0530
Click here to add this to my saved trials
Albuquerque, New Mexico 87109
Principal Investigator: Thomas M. Schroeder
Phone: 505-272-0530
Click here to add this to my saved trials
1500 East Medical Center Drive
Ann Arbor, Michigan 48109
Ann Arbor, Michigan 48109
800-865-1125
Principal Investigator: Daniel E. Spratt
University of Michigan Comprehensive Cancer Center The U-M Comprehensive Cancer Center's mission is the conquest...
Click here to add this to my saved trials
Atlanta, Georgia 30303
Principal Investigator: Ashesh B. Jani
Phone: 404-489-9164
Click here to add this to my saved trials
Atlanta, Georgia 30322
Principal Investigator: Ashesh B. Jani
Phone: 404-778-1868
Click here to add this to my saved trials
Atlanta, Georgia 30342
Principal Investigator: Ashesh B. Jani
Phone: 412-339-5294
Click here to add this to my saved trials
550 Peachtree St NE
Atlanta, Georgia 30308
Atlanta, Georgia 30308
(404) 686-4411
Principal Investigator: Ashesh B. Jani
Phone: 888-946-7447
Emory University Hospital Midtown Emory University Hospital Midtown is a 511-bed community-based, acute care teaching...
Click here to add this to my saved trials
1968 Peachtree Rd NW
Atlanta, Georgia 30309
Atlanta, Georgia 30309
(404) 605-5000
Principal Investigator: Adam W. Nowlan
Phone: 404-425-7943
Piedmont Hospital For more than a century, Piedmont Healthcare has been a recognized leader in...
Click here to add this to my saved trials
12605 East 16th Avenue
Aurora, Colorado 80045
Aurora, Colorado 80045
720-848-0000
Principal Investigator: Thomas J. Pugh
Phone: 720-848-0650
University of Colorado Hospital, Site Top medical professionals, superior medicine and progressive change make University...
Click here to add this to my saved trials
Baltimore, Maryland 21229
Principal Investigator: Richard S. Hudes
Phone: 410-368-2910
Click here to add this to my saved trials
Bath, Maine 04530
Principal Investigator: Matthew D. Cheney
Phone: 412-339-5294
Click here to add this to my saved trials
Beachwood, Ohio 44122
Principal Investigator: Rodney J. Ellis
Phone: 800-641-2422
Click here to add this to my saved trials
Bemidji, Minnesota 56601
Principal Investigator: Preston D. Steen
Phone: 218-333-5000
Click here to add this to my saved trials
Berkeley, California 94704
Principal Investigator: Christopher U. Jones
Phone: 415-209-2686
Click here to add this to my saved trials
Berlin, Vermont 05602
Principal Investigator: Nataniel H. Lester-Coll
Phone: 802-225-5400
Click here to add this to my saved trials
300 N. Seventh St.
Bismarck, North Dakota 58501
Bismarck, North Dakota 58501
(701) 323-6000
Principal Investigator: Preston D. Steen
Phone: 701-323-5760
Sanford Bismarck Medical Center Whether your stay in our hospital is one day for same...
Click here to add this to my saved trials
Boston, Massachusetts 02118
Principal Investigator: Ariel E. Hirsch
Phone: 617-638-8265
Click here to add this to my saved trials
Brookfield, Wisconsin 53045
Principal Investigator: Lewis A. Rosenberg
Phone: 262-785-2273
Click here to add this to my saved trials
Burlington, Vermont 05405
Principal Investigator: Nataniel H. Lester-Coll
Phone: 802-656-4101
Click here to add this to my saved trials
Click here to add this to my saved trials
789 Mt Auburn Rd
Cape Girardeau, Missouri 63703
Cape Girardeau, Missouri 63703
(573) 519-4725
Principal Investigator: Bryan A. Faller
Phone: 573-651-5550
Southeast Cancer Center SoutheastHEALTH is a far-reaching network of providers and facilities including Southeast Hospital...
Click here to add this to my saved trials
Chadds Ford, Pennsylvania 19317
Principal Investigator: Gregory A. Masters
Phone: 302-623-4450
Click here to add this to my saved trials
Click here to add this to my saved trials
171 Ashley Avenue
Charleston, South Carolina 29425
Charleston, South Carolina 29425
843-792-1414
Principal Investigator: David T. Marshall
Phone: 843-792-9321
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
Click here to add this to my saved trials
Clarkston, Michigan 48346
Principal Investigator: Frank A. Vicini
Phone: 248-338-0663
Click here to add this to my saved trials
5680 Bow Pointe Drive
Clarkston, Michigan 48346
Clarkston, Michigan 48346
Principal Investigator: Neal H. Bhatt
Phone: 313-576-9790
Click here to add this to my saved trials
10900 Euclid Ave
Cleveland, Ohio 44106
Cleveland, Ohio 44106
216-368-2000
Principal Investigator: Rodney J. Ellis
Phone: 800-641-2422
Case Western Reserve Univ Continually ranked among America's best colleges, Case Western Reserve University has...
Click here to add this to my saved trials
18101 Lorain Avenue
Cleveland, Ohio 44111
Cleveland, Ohio 44111
216.476.7000
Principal Investigator: Lanea Keller
Phone: 866-223-8100
Cleveland Clinic Cancer Center at Fairview Hospital Fairview Hospital is a 488-bed hospital located at...
Click here to add this to my saved trials
1400 East Boulder Street
Colorado Springs, Colorado 80909
Colorado Springs, Colorado 80909
Principal Investigator: Thomas J. Pugh
Phone: 719-365-2406
Click here to add this to my saved trials
Colorado Springs, Colorado 80920
Principal Investigator: Thomas J. Pugh
Phone: 719-364-6700
Click here to add this to my saved trials
Columbus, Ohio 43210
Principal Investigator: Dayssy A. Diaz Pardo
Phone: 800-293-5066
Click here to add this to my saved trials
100 North Academy Avenue
Danville, Pennsylvania 17822
Danville, Pennsylvania 17822
570-271-6211
Principal Investigator: Fiori Alite
Phone: 570-271-5251
Geisinger Medical Center Since 1915, Geisinger Medical Center has been known as the region’s resource...
Click here to add this to my saved trials
Dearborn, Michigan 48124
Principal Investigator: Zachary A. Seymour
Phone: 313-593-8090
Click here to add this to my saved trials
2300 N Edward St
Decatur, Illinois 62526
Decatur, Illinois 62526
(217) 876-8121
Principal Investigator: Bryan A. Faller
Phone: 217-876-4740
Decatur Memorial Hospital An American flag bearing only 48 stars waved above Decatur Memorial Hospital...
Click here to add this to my saved trials
4160 John R St #2122
Detroit, Michigan 48201
Detroit, Michigan 48201
(313) 833-1785
Principal Investigator: Neal H. Bhatt
Phone: 313-576-9790
Wayne State University/Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
Click here to add this to my saved trials
Drexel Hill, Pennsylvania
Principal Investigator: Rachelle M. Lanciano
Phone: 610-284-8237
Click here to add this to my saved trials
Effingham, Illinois 62401
Principal Investigator: Bryan A. Faller
Phone: 217-876-4740
Click here to add this to my saved trials
Elyria, Ohio 44035
Principal Investigator: Rodney J. Ellis
Phone: 800-641-2422
Click here to add this to my saved trials
820 4th St N
Fargo, North Dakota 58102
Fargo, North Dakota 58102
(701) 234-6161
Principal Investigator: Preston D. Steen
Phone: 701-234-6161
Roger Maris Cancer Center Sanford Health is an integrated health system headquartered in the Dakotas...
Click here to add this to my saved trials
28595 Orchard Lake Road
Farmington Hills, Michigan 48334
Farmington Hills, Michigan 48334
Principal Investigator: Frank A. Vicini
Phone: 248-338-0663
Click here to add this to my saved trials
Farmington Hills, Michigan 48334
Principal Investigator: Neal H. Bhatt
Phone: 313-576-9790
Click here to add this to my saved trials
Flint, Michigan 48532
Principal Investigator: Neal H. Bhatt
Phone: 313-576-9790
Click here to add this to my saved trials
1024 S Lemay Ave
Fort Collins, Colorado 80524
Fort Collins, Colorado 80524
(970) 495-7000
Principal Investigator: Thomas J. Pugh
Phone: 970-297-6150
Poudre Valley Hospital A 270-bed regional medical center offering a wide array of treatments, surgeries,...
Click here to add this to my saved trials
2200 Randallia Drive
Fort Wayne, Indiana 46805
Fort Wayne, Indiana 46805
Principal Investigator: Brian K. Chang
Phone: 260-373-8888
Click here to add this to my saved trials
Fort Wayne, Indiana 46845
Principal Investigator: Brian K. Chang
Phone: 877-784-4673
Click here to add this to my saved trials
Franklin, Wisconsin 53132
Principal Investigator: Lewis A. Rosenberg
Phone: 262-785-2273
Click here to add this to my saved trials
Gilbert, Arizona 85297
Principal Investigator: Terry T. Lee
Phone: 480-922-4600
Click here to add this to my saved trials
Glenwood Springs, Colorado 81601
Principal Investigator: Peter J. Rossi
Phone: 970-384-7570
Click here to add this to my saved trials
100 Michigan St NE
Grand Rapids, Michigan 49503
Grand Rapids, Michigan 49503
(616) 391-1774
Principal Investigator: Kathleen J. Yost
Phone: 616-391-1230
Spectrum Health at Butterworth Campus Butterworth Hospital is one of four facilities that make up...
Click here to add this to my saved trials
1117 29th St S
Great Falls, Montana 59405
Great Falls, Montana 59405
(406) 771-7300
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
Benefis Healthcare- Sletten Cancer Institute Benefis Hospitals has 516 beds at its two campuses (that...
Click here to add this to my saved trials
2845 Greenbrier Rd
Green Bay, Wisconsin 54311
Green Bay, Wisconsin 54311
(920) 288-8000
Principal Investigator: Ellen L. Ziaja
Phone: 414-302-2304
Aurora BayCare Medical Center Aurora BayCare Medical Center is a 167-bed, full-service hospital serving the...
Click here to add this to my saved trials
Greenbrae, California 94904
Principal Investigator: Lloyd T. Miyawaki
Phone: 415-925-7325
Click here to add this to my saved trials
Greenville, South Carolina 29605
Principal Investigator: Michael D. Zurenko
Phone: 864-241-6251
Click here to add this to my saved trials
Greenville, South Carolina 29615
Principal Investigator: Michael D. Zurenko
Phone: 864-241-6251
Click here to add this to my saved trials
Greenwood, South Carolina 29646
Principal Investigator: David T. Marshall
Phone: 864-725-4771
Click here to add this to my saved trials
Greer, South Carolina 29650
Principal Investigator: Michael D. Zurenko
Phone: 864-241-6251
Click here to add this to my saved trials
Hilton Head Island, South Carolina 29926
Principal Investigator: Howard A. Zaren
Phone: 912-819-5704
Click here to add this to my saved trials
Hines, Illinois 60141
Principal Investigator: Abhishek A. Solanki
Phone: 708-202-8387
Click here to add this to my saved trials
Click here to add this to my saved trials
8111 South Emerson Avenue
Indianapolis, Indiana 46237
Indianapolis, Indiana 46237
Principal Investigator: Valeri Goutsouliak
Phone: 317-528-7060
Click here to add this to my saved trials
310 Sunnyview Ln
Kalispell, Montana 59901
Kalispell, Montana 59901
(406) 752-5111
Principal Investigator: Benjamin T. Marchello
Phone: 406-969-6060
Kalispell Regional Medical Center Nestled in the beautiful Flathead Valley of Northwestern Montana, Kalispell Regional...
Click here to add this to my saved trials
Kansas City, Kansas 66160
Principal Investigator: Xinglei Shen
Phone: 913-945-7552
Click here to add this to my saved trials
1915 White Ave.
Knoxville, Tennessee 37916
Knoxville, Tennessee 37916
(865) 541-1678
Principal Investigator: Grant M. Clark
Phone: 865-331-1812
Thompson Cancer Survival Center The Thompson Cancer Survival Center Downtown facility has pioneered many advances...
Click here to add this to my saved trials
3855 Health Sciences Dr,
La Jolla, California 92093
La Jolla, California 92093
(858) 822-6100
Principal Investigator: Brent S. Rose
Phone: 858-822-5354
UC San Diego Moores Cancer Center Established in 1978, UC San Diego Moores Cancer Center...
Click here to add this to my saved trials
Lansing, Michigan 48910
Principal Investigator: Neal H. Bhatt
Phone: 313-576-9790
Click here to add this to my saved trials
1 Medical Center Dr
Lebanon, New Hampshire 03756
Lebanon, New Hampshire 03756
(603) 650-5000
Principal Investigator: Alan C. Hartford
Phone: 800-639-6918
Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
Click here to add this to my saved trials
Lewisburg, Pennsylvania 17837
Principal Investigator: Fiori Alite
Phone: 570-374-8555
Click here to add this to my saved trials
1983 Marengo St
Los Angeles, California 90033
Los Angeles, California 90033
(323) 226-2622
Principal Investigator: Leslie Ballas
Phone: 323-865-0451
Los Angeles County-USC Medical Center The origins of LAC+USC Medical Center date back to 1878,...
Click here to add this to my saved trials
1441 Eastlake Ave
Los Angeles, California 90033
Los Angeles, California 90033
(323) 865-3000
Principal Investigator: Leslie Ballas
Phone: 323-865-0451
U.S.C./Norris Comprehensive Cancer Center The USC Norris Comprehensive Cancer Center, located in Los Angeles, is...
Click here to add this to my saved trials
Mansfield, Ohio 44906
Principal Investigator: Lanea Keller
Phone: 866-223-8100
Click here to add this to my saved trials
Mayfield Heights, Ohio 44124
Principal Investigator: Lanea Keller
Phone: 866-223-8100
Click here to add this to my saved trials
2160 South 1st Avenue
Maywood, Illinois 60153
Maywood, Illinois 60153
(888) 584-7888
Principal Investigator: Abhishek A. Solanki
Phone: 708-226-4357
Loyola University Medical Center Loyola University Health System is committed to excellence in patient care...
Click here to add this to my saved trials
5236 West University Drive
McKinney, Texas 75071
McKinney, Texas 75071
Principal Investigator: Vivek S. Kavadi
Phone: 972-542-8609
Click here to add this to my saved trials
Menomonee Falls, Wisconsin 53051
Principal Investigator: Colleen A. Lawton
Phone: 262-257-5100
Click here to add this to my saved trials
9485 Mentor Ave
Mentor, Ohio 44060
Mentor, Ohio 44060
(440) 205-5755
Principal Investigator: Rodney J. Ellis
Phone: 800-641-2422
Lake University Ireland Cancer Center Lake Health is a private, not-for-profit leader in community health...
Click here to add this to my saved trials
Metairie, Louisiana 70006
Principal Investigator: Scott E. Delacroix
Phone: 504-210-3539
Click here to add this to my saved trials
Milwaukee, Wisconsin 53215
Principal Investigator: Ellen L. Ziaja
Phone: 412-339-5294
Click here to add this to my saved trials
9200 W Wisconsin Ave
Milwaukee, Wisconsin 53226
Milwaukee, Wisconsin 53226
(414) 805-3666
Principal Investigator: Colleen A. Lawton
Phone: 414-805-4380
Froedtert and the Medical College of Wisconsin Froedtert Health combines with the Medical College of...
Click here to add this to my saved trials
Morgantown, West Virginia 26505
Principal Investigator: Malcolm D. Mattes
Phone: 304-293-7374
Click here to add this to my saved trials
Mount Clemens, Michigan 48043
Principal Investigator: Neal H. Bhatt
Phone: 313-576-9790
Click here to add this to my saved trials
5121 S Cottonwood St
Murray, Utah 84157
Murray, Utah 84157
(801) 507-7000
Principal Investigator: R. J. Lee
Phone: 801-507-3950
Intermountain Medical Center Intermountain Medical Center is one of the most technologically advanced and patient-friendly...
Click here to add this to my saved trials
New Haven, Connecticut 6520
(203) 432-4771
Principal Investigator: James B. Yu
Phone: 203-785-5702
Yale University Yale's roots can be traced back to the 1640s, when colonial clergymen led...
Click here to add this to my saved trials
New York, New York 10016
Principal Investigator: Peter B. Schiff
Phone: 212-263-4434
Click here to add this to my saved trials
Newark, Delaware 19713
Principal Investigator: Gregory A. Masters
Phone: 302-623-4450
Click here to add this to my saved trials
4755 Ogletown-Stanton Road
Newark, Delaware 19718
Newark, Delaware 19718
302-733-1000
Principal Investigator: Gregory A. Masters
Phone: 302-623-4450
Christiana Care Health System - Christiana Hospital A 913-bed, 1.3-million-square-foot, modern facility in Newark, Delaware,...
Click here to add this to my saved trials
150 Kingsley Lane
Norfolk, Virginia 23505
Norfolk, Virginia 23505
Principal Investigator: William J. Irvin
Phone: 804-893-8611
Click here to add this to my saved trials
600 Gresham Dr
Norfolk, Virginia 23507
Norfolk, Virginia 23507
(757) 388-3000
Principal Investigator: Mark E. Shaves
Phone: 757-388-2406
Sentara Norfolk General Hospital Sentara Norfolk General Hospital is recognized as the number one ranked...
Click here to add this to my saved trials
940 NE 13th St
Oklahoma City, Oklahoma 73190
Oklahoma City, Oklahoma 73190
(405) 271-6458
Principal Investigator: J. S. Thompson
Phone: 405-271-8777
University of Oklahoma Health Sciences Center The OU Health Sciences Center is composed of seven...
Click here to add this to my saved trials
Oshkosh, Wisconsin 54904
Principal Investigator: Robert R. Kohl
Phone: 920-831-8900
Click here to add this to my saved trials
Overland Park, Kansas 66210
Principal Investigator: Xinglei Shen
Phone: 913-945-7552
Click here to add this to my saved trials
255 W Lancaster Ave
Paoli, Pennsylvania 19301
Paoli, Pennsylvania 19301
(484) 565-1000
Principal Investigator: Albert S. DeNittis
Phone: 484-476-2649
Paoli Memorial Hospital Paoli is recognized regionally and nationally for outstanding medical and surgical services,...
Click here to add this to my saved trials
Peoria, Arizona 85381
Principal Investigator: Terry T. Lee
Phone: 623-773-2873
Click here to add this to my saved trials
Peoria, Illinois 61637
Principal Investigator: Bryan A. Faller
Phone: 309-243-3605
Click here to add this to my saved trials
Petoskey, Michigan 49770
Principal Investigator: Neal H. Bhatt
Phone: 313-576-9790
Click here to add this to my saved trials
111 S 11th St
Philadelphia, Pennsylvania 19107
Philadelphia, Pennsylvania 19107
(215) 955-6000
Principal Investigator: Robert B. Den
Phone: 215-955-6084
Thomas Jefferson University Hospital Our hospitals in Center City Philadelphia share a 13-acre campus with...
Click here to add this to my saved trials
Click here to add this to my saved trials