Metoclopramide for Post Traumatic Headache



Status:Recruiting
Conditions:Migraine Headaches
Therapuetic Areas:Neurology
Healthy:No
Age Range:18 - Any
Updated:12/14/2017
Start Date:August 1, 2017
End Date:August 2019

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A Randomized Placebo Controlled Trial of IV Metoclopramide for Acute Post-traumatic Headache

Nearly 1.5 million patients present to US emergency departments annually following head
trauma. Headache is a frequent symptom of victims of head trauma. The purpose of this study
is to see if an intravenous medication called metoclopramide can improve the symptoms of
patients with acute post-traumatic headache.


Inclusion Criteria:

Included patients will be adults who meet International Classification of Headache
Disorders criteria for acute post-traumatic headache. These are as follows:

- Traumatic injury to the head has occurred

- Headache has developed within 7 days of injury to the head

- Headache is not better accounted for by another diagnosis (eg, previous history of
migraine or tension-type headache)

The headache must be rated as moderate or severe in intensity at the time of initial
evaluation.

Exclusion Criteria:

Patients will be excluded if more than ten days have elapsed since the head trauma, if the
headache has already been treated with an anti-dopaminergic medication, or for medication
contra-indications including pheochromocytoma, seizure disorder, Parkinson's disease, use
of MAO inhibitors, and use of anti-rejection transplant medications.
We found this trial at
1
site
3550 Jerome Avenue
Bronx, New York 10467
(718) 920-4321
Phone: 718-920-6626
Montefiore Medical Center As the academic medical center and University Hospital for Albert Einstein College...
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mi
from
Bronx, NY
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