Prevention of Early Postoperative Decline



Status:Active, not recruiting
Conditions:Cognitive Studies, Hospital, Neurology, Psychiatric
Therapuetic Areas:Neurology, Psychiatry / Psychology, Other
Healthy:No
Age Range:60 - 90
Updated:1/31/2019
Start Date:November 2016
End Date:May 2019

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The purpose of this trial is to determine whether using a brain training program in the time
leading up to as well as after heart surgery will reduce confusion and cognitive loss that
can occur after surgery.

Randomized, controlled pilot study with a convenience sample of 45 adult cardiac surgical
patients. The main intervention to be studied will be the use of a neurocognitive training
program (Lumosity) for 10 days preoperatively, and then for four weeks postoperatively. The
prescribed regimen of training will focus on the areas of cognitive function most commonly
affected in the postoperative period, including working memory, attention, and processing
speed. Patients in the control arm will undergo current standard cardiac surgical
postoperative care and will be asked to refrain from obtaining a Lumosity account.

Inclusion Criteria:

- Adult patients undergoing cardiac surgery age 60-90

- Cardiac surgery scheduled at least 10 days from enrollment

- High school education level or equivalent

Exclusion Criteria:

- Preexisting psychiatric illness

- History of cerebrovascular event or seizure

- Non English speakers

- Baseline severe cognitive dysfunction including Alzheimer's, Parkinson's, or other
severe forms of dementia

- Significant visual impairment

- Enrollment in another study involving cognition
We found this trial at
1
site
330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Phone: 617-754-3189
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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from
Boston, MA
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