Analyzing the Composition of Tears to Identify Cancer

Specifically, this study will compare the protein profile in tear fluid from patients with
breast, ovarian or colon cancer versus "normal male and female patients" for differences
that show promise as a diagnostic indicator. If such differences can be found, then their
diagnostic potential will be assessed and developed further in a subsequent study. The
long-term goal of this project will be to develop a screening tool for the detection of
breast and/or other cancers.

Inclusion Criteria:

- Female or male, 18-100 years old

- Patients who present for a routine check-up

- Patients who present for the evaluation of an abnormal exam or test (mammogram,
ultrasound, MRI, PET, etc.)

- May or may not have a mass present

- Patients who present for the evaluation of a palpable lump or mass

- Patients may be pre or post biopsy for a mass, as long as there is a portion of the
mass remaining

Exclusion Criteria:

- Patient < 18 y/o or > 100 y/o

- Concurrent eye infection or trauma

- Active conjunctivitis

- Abnormal production of tears (too much or too little)