Sciatic Technique Comparison of Nerve Blockade for Pain Control Following Hamstring Autograft Harvest in Adolescents

SPECIFIC AIM 1. The first aim of the study is to explore the impact of sciatic PNB technique
on hamstring donor site pain control postoperatively.

H1.a. The extended duration of analgesia offered by continuous sciatic PNB decreases pain
scores during the initial 72 hours following hamstring autograft harvest when compared to
single-injection sciatic PNB.

H1.b. The extended duration of analgesia offered by continuous sciatic PNB decreases oral
pain medication use during the initial 72 hours following hamstring autograft harvest when
compared to single-injection sciatic PNB.

H1.c. The extended duration of analgesia offered by continuous sciatic PNB decreases the
incidence of unplanned admission due to poor pain control during the initial 72 hours
following hamstring autograft harvest when compared to single-injection sciatic PNB.

SPECIFIC AIM 2. The second aim of the study is to explore the impact of sciatic PNB technique
on active knee flexion postoperatively.

H2. The extended duration of analgesia offered by continuous sciatic PNB does not delay
active knee flexion during the initial 72 hours following hamstring autograft harvest when
compared to single-injection sciatic PNB.

SPECIFIC AIM 3. The third aim of the study is to explore the impact of sciatic PNB technique
on patient satisfaction with postoperative pain control.

H3.1. The extended duration of analgesia offered by continuous sciatic PNB improves patient
satisfaction during the initial 72 hours following hamstring autograft harvest when compared
to single-injection sciatic PNB.

Inclusion Criteria:

A subject may be INCLUDED in this study if:

1. The subject is male or female;

2. The subject is of any racial or ethnic group;

3. The subject is age 10 years to 18 years (inclusive);

4. The subject is scheduled for the following: Unilateral ACL reconstruction with a
hamstring autograft under general anesthesia on an outpatient basis, and not being
performed in conjunction with any other surgical procedures;

5. The subject is American Society of Anesthesiologists (ASA) patient classification
I-II;

6. The subject or legally authorized representative has consented to femoral and sciatic
peripheral nerve blockade for the procedure and the consent for peripheral nerve
blockade has been obtained by a clinician (MD, DO, CRNA or APN) authorized to obtain
consent;

7. The subject's legally authorized representative has given written informed consent to
participate in the study and when appropriate, the subject has given assent or consent
to participate.

Exclusion Criteria:

A subject will be EXCLUDED from this study if:

1. Additional surgical procedures are being performed concurrently;

2. The subject is ASA classification > II;

3. The subject has pre-existing allergies to amide local anesthetics;

4. The subject receives sedation preoperatively;

5. The subject is schedule for overnight hospital admission;

6. The subject has any other condition, which in the opinion of the principal
investigator, would not be suitable for participation in the study, including but not
limited to coagulopathy, preexisting central or peripheral nervous systems disorders,
and local infection or sores at the anticipated site of needle insertion;

7. Unsuccessful PNB or CPI catheter placement occurs during the study. -