Validation of the Gated Blood Pool SPECT: ERNA vs 3D Echo



Status:Completed
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:4/2/2016
Start Date:February 2005
End Date:January 2011
Contact:Carol Akirav, MSc
Email:carol.akirav@yale.edu
Phone:203-785-2429

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Trial Summary
Trial Overview
Inclusion Criteria

Validation of the Gated Blood Pool SPECT: Comparison to ERNA and 3-dimensional Echocardiography.

This research study is designed to evaluate the accuracy of the techniques that are used to
analyze heart function. The main purpose of this study is to analyze and compare three
different methods of assessment of regional and overall heart function.

The purpose of the present study is to establish the reproducibility and to validate gated
blood pool SPECT imaging with application of attenuation correction (ACGBS) in evaluation of
left ventricular regional and global function and volumes, by direct comparison with
Equilibrium Radionuclide Angiocardiography (ERNA) and 3-dimensional ECHO (3DE).

Inclusion Criteria:

- All patients scheduled for routine clinically requested ERNA study for ejection
fraction measurement at the Yale University Cardiovascular Nuclear Imaging Laboratory
are eligible to be enrolled in the study.

Exclusion Criteria:

- Unstable medical condition preventing additional imaging.

- Weight greater than 300lbs, prohibiting imaging on the SPECT/CT imaging system.

- Patients with intracardiac shunts, emphysema or previously demonstrated allergies to
octafluoropropane (the gas in the microbubbles), will not receive intravenous
contrast during 3 DE image acquisition.
We found this trial at
1
site
Yale-New Haven Hospital
20 York St, N20 York St,
New Haven, Connecticut 06520
(203) 688-4242
Yale-New Haven Hospital Relying on the skill and expertise of more than 4,500 university and...
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New Haven, CT
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