Aggressive Versus Moderate Glycemic Control in Diabetic Coronary Bypass Patients



Status:Completed
Conditions:Endocrine
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 90
Updated:7/11/2015
Start Date:October 2006
End Date:June 2014
Contact:Harold L Lazar
Email:harold.lazar@bmc.org
Phone:617-638-7352

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Impact of Aggressive Versus Moderate Glycemic Control on Clinical Outcomes Following Coronary Artery Bypass Graft Surgery in Diabetic Patients

entGlycemic control has been found to improve clinical outcomes following Coronary Bypass
Surgery. This study tests the hypothesis that obtaining tighter glycemic
control(80-120mg/dl) as opposed to more moderate control (120-180mg/dl) will further improve
outcomes.

150 diabetic patients will be randomized to achieve aggressive glycemic control
(80-120mg/dl) vs moderate control (120-180mg/dl) using intravenous insulin infusions
beginning at anesthetic induction and continuing for 18 hours following surgery.

Inclusion Criteria:

- All diabetic patients undergoing Coronary Bypass Surgery

Exclusion Criteria:

- Patients with hepatic and renal failure
We found this trial at
1
site
1 Boston Medical Center Pl
Boston, Massachusetts 02118
617.638.8000
Boston Med Center Boston Medical Center (BMC) is a 496-bed academic medical center located in...
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mi
from
Boston, MA
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