The Impact of Transcutaneous Spinal Cord Stimulation (TSCS) and Gait Training on Walking Function in Patients With Spinal Cord Injury
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Hospital, Hospital, Orthopedic |
| Therapuetic Areas: | Orthopedics / Podiatry, Other |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 2/2/2019 |
| Start Date: | January 5, 2017 |
| End Date: | December 31, 2019 |
Aim 1: Determine the neurophysiologic impact of Transcutaneous Spinal Cord Stimulation (TSCS)
within a single session. The investigators hypothesize that subjects will demonstrate
increased volitional muscle activity and strength with TSCS. This will be assessed by surface
EMG and hand-held dynamometry of the dominant-side quadriceps muscle during maximum
volitional contraction (MVC) and measurement of gait speed. Subjects will be tested in both
TSCS and sham conditions.
Aim 2: Determine the impact of TSCS and gait training on walking function. The investigators
hypothesize that concurrent TSCS and gait training will augment walking function in subjects
with iSCI, as compared to gait training alone. Subjects will participate in an eight-week
program of gait training with TSCS and be assessed with clinically relevant outcome measures,
to include the Timed Up and Go, 10-Meter Walk Test, Walking Index for Spinal Cord Injury II,
and 6-Minute Walk Test.
within a single session. The investigators hypothesize that subjects will demonstrate
increased volitional muscle activity and strength with TSCS. This will be assessed by surface
EMG and hand-held dynamometry of the dominant-side quadriceps muscle during maximum
volitional contraction (MVC) and measurement of gait speed. Subjects will be tested in both
TSCS and sham conditions.
Aim 2: Determine the impact of TSCS and gait training on walking function. The investigators
hypothesize that concurrent TSCS and gait training will augment walking function in subjects
with iSCI, as compared to gait training alone. Subjects will participate in an eight-week
program of gait training with TSCS and be assessed with clinically relevant outcome measures,
to include the Timed Up and Go, 10-Meter Walk Test, Walking Index for Spinal Cord Injury II,
and 6-Minute Walk Test.
Inclusion Criteria:
- 18-65 years old
- >1 year post SCI
- Non-progressive SCI
- Neurological level above T10
- Tolerates upright position for >30 minutes
- Medically stable (no hospitalizations in last 3 months)
- Able to comply with procedures and follow up
- Are legally able to make their own health care decisions
Exclusion Criteria:
- Progressive SCI/D (MS, ALS, ADEM, etc.)
- Open wounds at stimulation site
- Pregnant women
- ROM limitations impacting gait training
- Cardiac pacemaker/defibrillator
- Active cancer diagnosis
- Currently receiving TSCS
- Evidence of uncontrolled autonomic dysreflexia
- Non-English speaking subjects will not be targeted
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