Barley and Rice Mixture Effects on Blood Glucose



Status:Completed
Conditions:Endocrine
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 50
Updated:1/3/2018
Start Date:February 13, 2017
End Date:September 18, 2017

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β-glucan Rich Barley and Rice Mixes and Post-prandial Glycemia - a Dose Response Study

The purpose of this research was to investigate 5 different formulations of whole grain
barley and refined white rice against a control of white bread on post-prandial glycemic
response, as well as self-reported hunger/satiety in a randomized cross-over trial.

Beta-glucan-rich barley has been shown to improve glycemic response, reduce hunger and
increase satiety. Nutrient-dense grain mixtures that include a new cultivar of barley
(Sustagrain, Ardent Mills, LLC) with exceptionally high dietary fiber content may help
individuals meet their dietary fiber needs while minimizing the rapid increase in blood
glucose following the consumption of a refined grain product. The primary objective of this
study was to compare the effects of five different test meals containing varying amounts of
whole-grain barley and refined white rice to white bread on post-prandial blood glucose
concentrations. A secondary aim was to evaluate changes in self-reported hunger and satiety
following the consumption of each treatment. This study was a single-site, blinded,
randomized crossover trial among 24 healthy adults. Each participant consumed the following
treatments: 100% Sustagrain barley flakes, 100% Sustagrain steel cut barley , an 80/20
rice-steel cut Sustagrain barley mix, a 50/50 rice-steel cut Sustagrain barley mix, 100%
rice, and white bread.

Inclusion Criteria:

- Healthy, English speaking adults;

- BMI between 18 and 30 kg/m2

Exclusion Criteria:

- History of GI malabsorption diseases, food allergy or intolerance to gluten;

- Prediabetes, and/or diabetes, and/or treatment with diabetic medications for any
reason;

- Hypertension, hypothyroidism and other chronic disease that affects nutrient
metabolism;

- Any women pregnant or lactating, or expecting to become pregnant during the study;

- Individuals with a history of bleeding disorders
We found this trial at
1
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Phoenix, Arizona 85004
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Phoenix, AZ
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