Detection, Education, Research and Decolonization Without Isolation in Long-term Care Facilities



Status:Completed
Conditions:Hospital
Therapuetic Areas:Other
Healthy:No
Age Range:18 - Any
Updated:2/15/2018
Start Date:October 2010
End Date:November 2014

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Detection, Education, Research and Decolonization Without Isolation in Long-term Care to Control(DERAIL)MRSA

Our hypothesis for the DERAIL MRSA program is that one can safely remove the colonization
risk from nearly all residents (patients) in a way that does not interfere with the desired
life-style for persons in these facilities and thereby reduce the risk of infection and lower
the cost of care by avoiding preventable disease.

The primary endpoint will be measuring the reduction in MRSA colonization prevalence
(percentage rate) in the intervention arm as compared to the control arm. One secondary
endpoint is to compare the rate of MRSA disease (number of infections per 1,000 patients and
10,000 patient days) in the intervention and control arms. The other secondary endpoint is to
determine the cost of MRSA screening and decolonization and compare it to the cost of MRSA
disease treatment (both medication cost and the expense of any needed hospitalization for
therapy of MRSA infection therapy) in the control arm. Achieving our primary goal of MRSA
control will also demonstrate two secondary goals wthe investigators aim to achieve: one
being that a scientific, planned approach to the issue of specific healthcare-associated
infection in LTCFs can resolve these problems and the other that a partnership between acute
and long-term care (e.g., ongoing relationship spanning at least 5 years) is beneficial in
dealing with patient safety and quality practices across the United Sates Healthcare
continuum.

Inclusion Criteria:

- All patients in 18 LTCF nursing units randomly selected as intervention or control
units

Exclusion Criteria:

- Patients that choose not to be included in the program
We found this trial at
1
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Evanston, IL
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