CSE v. Epidural for Postpartum Depression
| Status: | Recruiting |
|---|---|
| Conditions: | Depression, Depression, Women's Studies |
| Therapuetic Areas: | Psychiatry / Psychology, Reproductive |
| Healthy: | No |
| Age Range: | 18 - 50 |
| Updated: | 8/23/2018 |
| Start Date: | January 2017 |
| End Date: | July 2019 |
| Contact: | Grace Lim, MD MS |
| Email: | limkg2@upmc.edu |
| Phone: | 4126414260 |
Combined Spinal Epidural v. Epidural Labor Analgesia for Postpartum Depression Symptoms (COPE Trial): Pilot Randomized Control Trial
The purpose of this pilot prospective randomized control trial is to compare the initiation
of labor epidural analgesia by combined spinal epidural vs. epidural for the influence on
risk for postpartum depression symptoms. Investigators will randomize women to the receipt of
CSE or E during labor, after measuring baseline psychological, psychosocial, and
psychophysical factors related to pain and depression. The immediate research goals are to
understand whether the association between labor pain and PPD is modifiable through the use
of tailored anesthetic techniques.
of labor epidural analgesia by combined spinal epidural vs. epidural for the influence on
risk for postpartum depression symptoms. Investigators will randomize women to the receipt of
CSE or E during labor, after measuring baseline psychological, psychosocial, and
psychophysical factors related to pain and depression. The immediate research goals are to
understand whether the association between labor pain and PPD is modifiable through the use
of tailored anesthetic techniques.
Inclusion Criteria:
- Nulliparous (no prior childbirth)
- Singleton gestation
- Third trimester
- Healthy pregnancy
- English proficiency (surveys validated in English)
- Planned vaginal delivery
- Planning to use labor epidural analgesia
- Term delivery (>/= 37.0 weeks)
Exclusion Criteria:
- Severe maternal disease
- Severe fetal disease
- Delivery not at term (delivery prior to 37.0 weeks)
- Contraindications to neuraxial anesthesia known at the time of enrollment
- Cesarean delivery WITHOUT labor
- Planning to list infant for adoption
- Did not receive epidural analgesia (either CSE or E) for labor
We found this trial at
1
site
300 Halket St.
Pittsburgh, Pennsylvania 15213
Pittsburgh, Pennsylvania 15213
1-866-MyMagee (696-2433)
Phone: 412-641-2179
Magee-Womens Hospital of UPMC Magee-Womens Hospital of UPMC is a world-class center for both women's...
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