Circulating Tumor Cells in Solid Tumors



Status:Recruiting
Healthy:No
Age Range:18 - Any
Updated:9/27/2018
Start Date:December 9, 2011
End Date:December 1, 2022
Contact:Gaorav P Gupta, MD, PhD
Email:gaorav_gupta@med.unc.edu
Phone:919-945-4166

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Quantification and Characterization of Circulating Tumor Cells in Solid Tumors

The purpose of this study is to identify circulating tumor cells in patients with solid
tumors. Quantify and characterize these cells, collect patient information in regards to the
patient's cancer. Develop a database and a sample repository where future analysis could be
done.

The primary purpose of this correlative study is to create a prospective database documenting
the quantity and characterization of circulating tumor cells (CTCs) in solid tumor patients
as identified by a various laboratory techniques and analyses. The investigators are
developing this resource to provide data to achieve the following objectives: 1) correlate
CTCs with known prognostic factors, 2) correlate CTCs with burden of disease, 3) evaluate the
ability of CTCs to be used in the surveillance of disease recurrence, and 4) evaluate CTCs
ability to be used as a biomarker for treatment response.

Inclusion Criteria:

- Age ≥ 18 years of age

- Biopsy proven solid tumor malignancy

- Seen at UNC Chapel Hill Hospital and Health Care System

- Consents to abstraction of their medical records

- Signed an institutional review board (IRB)-approved informed consent document for this
protocol

Exclusion Criteria:

- < 18 years of age

- Dementia, altered mental status, incarceration or any psychiatric condition that would
prohibit the understanding or rendering of informed consent.
We found this trial at
1
site
Chapel Hill, North Carolina 27599
Phone: 984-974-8441
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Chapel Hill, NC
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