OSI-774 (Tarceva) Plus Gemcitabine in Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer.



Status:Completed
Conditions:Cancer, Cancer, Pancreatic Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - 120
Updated:1/12/2018
Start Date:November 29, 2001
End Date:January 15, 2004

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Trial Summary
Trial Overview
Inclusion Criteria

A Randomized Placebo Controlled Study of OSI-774 (Tarceva (TM)) Plus Gemcitabine in Patients With Locally Advanced, Unresectable or Metastatic Pancreatic Cancer

The purpose of this study is to determine if OSI-774 will improve overall survival when
combined with a standard dose of the chemotherapy drug gemcitabine, to individuals with
pancreatic cancer.


Inclusion Criteria:

Histologically or cytologically confirmed diagnosis of adenocarcinoma of the
pancreas;cancer which is unresectable, locally advanced or metastatic.

Must have evidence of disease (clinical or radiological). Male or female, 18 years or
older. Patients may have received prior radiation treatment for management of local disease
providing that disease progression has been documented.

All toxicities have resolved, and the last fraction of radiation treatment was completed at
least 4 weeks prior to randomization.

Patients may not have received prior chemotherapy, other then 5FU (+/- folic acid) or
gemcitabine given concurrently with radiation treatment as a 'radiosensitiser.'
We found this trial at
61
sites
Sarah Cannon Cancer Center
230 25th Ave N
Nashville, Tennessee 37203
(615) 329-7274
Sarah Cannon Cancer Center People who live with cancer
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Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland 21231
410-955-6190
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins The name Johns Hopkins has become synonymous...
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Florida Cancer Specialists
3840 Broadway
Fort Myers, Florida 33901
(239) 275-6400
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Univ of Minnesota
Minneapolis, Minnesota 55455
(612) 625-5000
Univ of Minnesota With a flagship campus in the heart of the Twin Cities, and...
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Tampa General Hospital
1 Tampa General Cir
Tampa, Florida 33606
(813) 844-7000
Tampa General Hospital In a diverse city known for its rich culture and beautiful beaches,...
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Annapolis Medical Specialists
2635 Riva Road
Annapolis, Maryland 21401
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Annapolis, MD
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Arlington Cancer Centre
Arlington, Texas 76012
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Arlington, TX
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Atlanta Cancer Center
Atlanta, Georgia 30342
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Atlanta, GA
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Southwest Regional Cancer Center
Austin, Texas 78705
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Austin, TX
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Sinai Hospital
Baltimore, Maryland 21215
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Baltimore, MD
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Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana 70809
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Baton Rouge, LA
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Green Mountain Oncology Group
Bennington, Vermont 05201
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Bennington, VT
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Alta Bates Comprehensive Cancer Center
Berkeley, California 94704
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Berkeley, CA
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'Odyssey Research Services
Bismarck, North Dakota 58501
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St. Elizabeth Medical Center
Boston, Massachusetts 02135
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Boston, MA
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New England Medical Center
Boston, Massachusetts 02111
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Boston, MA
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Hospital Italiano de Buenos Aires
Buenos Aires,
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Buenos Aires,
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Charleston Hematology Oncology, PA
Charleston, South Carolina 29403
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Presbyterian Hospital
200 Hawthorne Ln
Charlotte, North Carolina 28204
(704) 384-4000
Presbyterian Hospital At Novant Health Presbyterian Medical Center, we are welcoming a new era in...
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University Hospitals of Cleveland
11100 Euclid Ave
Cleveland, Ohio 44106
(216) 844-1000
University Hospitals of Cleveland The history of University Hospitals Case Medical Center is linked to...
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Hematology & Oncolgy Assoc of NE PA
1100 Meade Street
Dunmore, Pennsylvania 18512
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Dunmore, PA
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Arena Oncology Associates
600 Northern Boulevard
Great Neck, New York 11021
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Great Neck, NY
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New Hampshire Oncology-Hematology PA
Hooksett, New Hampshire 03106
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Hooksett, NH
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M.D. Anderson Cancer Center
Houston, Texas 77030
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Houston, TX
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University of Iowa Hospital and Clinics
Iowa City, Iowa 52242
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Iowa City, IA
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University of Kansas Medical Center
3901 Rainbow Blvd
Kansas City, Kansas 66160
(913) 588-5000
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
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Kansas City Oncology and Hematology Group
Kansas City, Missouri 64131
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University of Kentucky
Lexington, Kentucky
859) 257-9000
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St. Barnabas Medical Center
Livingston, New Jersey 07039
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Livingston, NJ
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Loma Linda University Cancer Institute
Loma Linda, California 92354
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Loma Linda, CA
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Metropolitan Hematology Oncology Medical Group
Los Angeles, California 90057
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UCLA Medical Center
757 Westwood Plaza
Los Angeles, California 90024
(310) 825-9111
UCLA Medical Center Founded in 1955, UCLA Medical Center became Ronald Reagan UCLA Medical Center...
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Norton Healthcare
Louisville, Kentucky 40207
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DeQuattro Community Cancer Center
73 Haynes Street
Manchester, Connecticut 06040
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Manchester, CT
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J Gurtler, Hematology and Oncology
3939 Houma Boulevard
Metairie, Louisiana 70006
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Metairie, LA
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Oncology/Hematology Group of South Florida
Miami, Florida 33176
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Miami, FL
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Oncology of Wisconsin
2900 West Oklahoma Avenue
Milwaukee, Wisconsin 53215
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Milwaukee, WI
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New Britain General Hospital
New Britain, Connecticut 06050
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New Britain, CT
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St. Luke's Roosevelt Hospital
New York, New York 10025
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New York University School of Medicine
550 1st Ave
New York, New York 10016
(212) 263-7300
New York University School of Medicine NYU School of Medicine has a proud history that...
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Eastern Connecticut Oncology
330 Washington Street
Norwich, Connecticut 06360
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Norwich, CT
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Ocala Oncology, P.A.
2494 Southwest 19th Avenue Road
Ocala, Florida 34471
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Ocala, FL
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Western Washington Oncology Inc.
Olympia, Washington 98502
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Olympia, WA
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Onc/Hem Associates of Central Illinois
301 Southwest Adams Street
Peoria, Illinois 61602
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Peoria, IL
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University of Pennsylvania Cancer Center
Philadelphia, Pennsylvania 19104
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Philadelphia, PA
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Pennsylvania Oncology Hematology Associates
Philadelphia, Pennsylvania 19106
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Philadelphia, PA
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Fox Chase Cancer Center
Philadelphia, Pennsylvania 19111
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Berkshire Hematology Oncology, PC
Pittsfield, Massachusetts 01201
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Chiles Research Cancer Center
Portland, Oregon 97213
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Portland, OR
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Hematology & Oncology Associates of Virginia, Ltd.
4501 Empire Court
Richmond, Virginia 23226
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Richmond, VA
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Interlakes Oncology/Hematology PC
Rochester, New York 14623
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Rochester, NY
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Kaiser Permanente
San Diego, California 92120
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San Diego, CA
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Hematology Oncology Associates of Illinois
Skokie, Illinois 60076
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Skokie, IL
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Highlands Oncology Group
Springdale, Arkansas 72764
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Springdale, AR
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Baystate Medical Center
759 Chestnut Street
Springfield, Massachusetts 01199
(413) 794 - 0000
Baystate Medical Center Baystate Medical Center (BMC), in Springfield, Massachusetts, is an academic, research, and...
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Carl and Dorothy Bennett Cancer Center
Stamford, Connecticut 06902
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Stony Brook University Hospital
Stony Brook, New York 11794
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Arizona Clinical Research Center
Tucson, Arizona 85712
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Tucson, AZ
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Tyler Hematology Oncology PA
Tyler, Texas 75701
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Carle Cancer Center
602 W University Ave
Urbana, Illinois 61801
(217) 383-3010
Carle Cancer Center Carle Cancer Center delivers comprehensive care through leading-edge technology and advanced research,...
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Southwest Washington Medical Center
Vancouver, Washington 98664
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