A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Adults With Stable Coronary Heart Disease



Status:Completed
Conditions:Peripheral Vascular Disease, Cardiology, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:45 - 80
Updated:2/7/2019
Start Date:December 13, 2017
End Date:November 9, 2018

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Trial Summary
Trial Overview
Inclusion Criteria

A Randomized, Double-blind, Placebo-controlled, Parallel-designed Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Subjects With Stable Coronary Heart Disease

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in
Adults With Stable Coronary Heart Disease

A Randomized, Double-blind, Placebo-controlled, Parallel-designed Study to Evaluate the
Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Subjects with Stable
Coronary Heart Disease

Inclusion Criteria:

- Diagnosis of stable coronary heart disease prior to screening

- Currently receiving high intensity statin(s)

Exclusion Criteria:

- Unstable cardiovascular conditions

- Any planned arterial revascularizations

- Fasting Laboratory values at screening: Triglycerides > 500 mg/dl, Low Density
Lipoprotein-Cholesterol > 100 mg/dL

- Any disease or condition or laboratory value that would place the subject at an
unacceptable risk.
We found this trial at
23
sites
Clinical Trial Facility in Anniston Alabama
Anniston, Alabama 36207
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Anniston, AL
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Clinical Trial Facility in Cincinnati Ohio
Cincinnati, Ohio
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Cincinnati, OH
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Clinical Trial Facility in El Cajon California
El Cajon, California 92020
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El Cajon, CA
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Clinical Trial Facility in Evanston Illinois
Evanston, Illinois
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Evanston, IL
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Clinical Trial Facility in Fargo North Dakota
Fargo, North Dakota 58122
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Fargo, ND
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Clinical Trial Facility in Fleming Island Florida
Fleming Island, Florida 32003
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Fleming Island, FL
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Clinical Trial Facility in Huntsville Alabama
Huntsville, Alabama 35801
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Huntsville, AL
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Clinical Trial Facility in Indianapolis Indiana
Indianapolis, Indiana 46202
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Indianapolis, IN
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Clinical Trial Facility in Jacksonville Florida
Jacksonville, Florida 32209
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Jacksonville, FL
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Clinical Trial Facility in Kingsport Tennessee
Kingsport, Tennessee 37660
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Kingsport, TN
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Clinical Trial Facility in Lincoln California
Lincoln, California 95648
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Lincoln, CA
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Clinical Trial Facility in Louisville Kentucky
Louisville, Kentucky 40202
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Louisville, KY
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Clinical Trial Facility in Marion Ohio
Marion, Ohio 43302
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Marion, OH
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Clinical Trial Facility in McAllen Texas
McAllen, Texas 78501
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McAllen, TX
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Clinical Trial Facility in Northridge California
Northridge, California 91328
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Northridge, CA
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Clinical Trial Facility in Oklahoma City Oklahoma
Oklahoma City, Oklahoma
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Oklahoma City, OK
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Clinical Trial Facility in Pembroke Pines Florida
Pembroke Pines, Florida 33028
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Pembroke Pines, FL
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Clinical Trial Facility in Port Orange Florida
Port Orange, Florida
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Port Orange, FL
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Clinical Trial Facility in Rapid City South Dakota
Rapid City, South Dakota 57701
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Rapid City, SD
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Clinical Trial Facility in San Antonio Texas
San Antonio, Texas 78224
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San Antonio, TX
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Clinical Trial Facility in Savannah Georgia
Savannah, Georgia 31406
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Savannah, GA
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Clinical Trial Facility in Stow Ohio
Stow, Ohio 44224
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Stow, OH
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Clinical Trial Facility in Waterbury Connecticut
Waterbury, Connecticut 06708
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Waterbury, CT
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