Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations

Inclusion Criteria:

- Female MSK patient, age 25 years or older (given that women under this age are not
generally recommended to receive BRCA1/2 genetic testing)

- Completed full sequence or targeted genetic testing with a clinically confirmed BRCA1
or BRCA2 deleterious mutation identified

- No personal history of breast cancer

- English-fluent; the surveys were designed and validated in English and are not
currently available in other languages. Translation of questionnaires into other
languages would require reestablishing the reliability and validity of these measures.
Therefore, participants must be able to communicate in English to complete the
surveys.

Exclusion Criteria:

- Previous receipt of any prophylactic mastectomy.

- Major psychiatric illness or cognitive impairment that in the judgment of the study
investigators or study staff would preclude study participation.

- Any patients who are unable to comply with the study procedures as determined by the
study investigators or study staff.