A Study Evaluate Aqueduct's Smart External Drain

In this two day clinical trial, subjects will be observed on Day 1 of study during their
routine treatment and using their already existing EVD. On Day 2 of study; subjects will be
switched to the Smart External Drain for monitoring and management of ICP and CSF

Inclusion Criteria:

1. Stable Neuro - examination on standard EVD assessed as Not Clinically Significant
(NCS) by PI or delegated Sub-I prior to study treatment.

2. GCS > 13 (minimum of E3V5M5) prior to study treatment.

3. Subject must be scheduled to have an EVD placed as part of routine management and for
a length of at least 48 hours. (e.g. in the setting of a tumor removal or treatment of
hydrocephalus)

4. Age 5-80.

5. Stable Vital Signs - Blood pressure (Systolic and Diastolic), Heart Rate, Respiratory
Rate and weight assessed as not clinically significant (NCS) and afebrile as per
PI/Sub-assessment. (Stable Vital signs will be re-assessed again prior to treatment
with the SED on Day 2)

6. Able to perform and follow simple commands (ex: sit up in bed, lay down in bed)

7. Pre-Study CT/MRI Imaging stable per PI Sub-I Assessment post ventriculostomy.

8. Able to stand

9. Able to obtain consent

Exclusion Criteria:

1. Refractory ICP or needing active ICP management

2. Unable to tolerate brief clamping of EVD (<5min)

3. Unable to follow simple commands

4. Unconscious

5. Anticoagulant Therapy

6. Known bleeding diathesis

7. Scalp Infection

8. In the opinion of the Investigator the subject is not a good study candidate