The Acute Effect of Egg-Based High Protein Meal on Hypertensive Response to Exercise



Status:Completed
Conditions:High Blood Pressure (Hypertension), Peripheral Vascular Disease
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:21 - 121
Updated:1/14/2018
Start Date:January 1, 2017
End Date:June 30, 2017

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The primary purpose of this study is to explore the effect of high versus normal egg-based
protein meals on acute exercise-induced elevated blood pressure.

This study is designed to assess BP changes during and post- exercise after consumption of a
test breakfast. The design consists of three visits. The first visit will assess each
participants aerobic exercise capacity (VO2 max). Visit 2 and 3 will be clinical testing days
where the subject will consume either the 13g or 30g protein breakfast in a randomized
cross-over manner and perform the exercise intervention. BP changes will be monitored before
and after breakfast consumption, during the exercise intervention,

Inclusion Criteria:

- Pre-hypertensive (systolic, 120-139 mm Hg; diastolic, 80-89 mm Hg

- Age ≥ 21

- Body weight <300 lb (136 kg)

- BMI between 20 and 34.9 kg/m2

- Fasting plasma glucose <6.1 mmol/L,

- total cholesterol <6.7 mmol/L

- LDL cholesterol <4.1 mmol/L

- TG <4.5 mmol/L

- No pre-existing or history of cardiovascular, renal or liver disease

- Not currently or previously (past 6 mo) consuming a weight-loss diet or other
special/non-balanced diets

- No weight loss/gain (±4.5 kg) within the past 6 mo

- No physical impairments preventing properly exercise execution

- No caffeine intake the day of testing

Exclusion Criteria:

- Hypertensive

- Body weight ≥ 300 lb

- BMI <20 or >35 kg/m2

- Pregnant or planning pregnancy

- Unwilling to consume study foods and beverages

- Fasting plasma glucose ≥6.1 mmol/L

- Total cholesterol ≥6.7 mmol/L

- LDL cholesterol ≥4.1 mmol/L

- TG ≥4.5 mmol/L

- acute illness

- smoking

- diabetic

- pre-existing or history of cardiovascular, renal or liver disease

- currently or previously (past 6 mo) consuming a weight-loss diet or other
special/non-balanced diets

- weight loss/gain (±4.5 kg) within the past 6 months

- physical impairments preventing properly exercise execution

- caffeine the day of testing
We found this trial at
1
site
West Lafayette, Indiana 47907
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mi
from
West Lafayette, IN
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