Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine for Breast Surgery
| Status: | Recruiting |
|---|---|
| Conditions: | Post-Surgical Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 8/10/2018 |
| Start Date: | December 1, 2017 |
| End Date: | August 30, 2019 |
| Contact: | William Hand, MD |
| Email: | whand@ghs.org |
| Phone: | (864) 522-3707 |
Pectoralis (II) Block With Liposomal Bupivacaine vs Bupivacaine Plus Dexamethasone for Mastectomy With Immediate Reconstruction
This is a randomized controlled pilot study evaluating length of pain control with either
liposomal bupivacaine or with bupivacaine plus decadron after PEC II injection in patients
having bilateral mastectomies with immediate reconstruction.
liposomal bupivacaine or with bupivacaine plus decadron after PEC II injection in patients
having bilateral mastectomies with immediate reconstruction.
This research hopes to determine the duration of patient-reported analgesia provided by
ultrasound guided PEC II field block injections. The design of the study randomly assigns the
side of injection of the study drugs into each patient. All patients are having bilateral
mastectomy with immediate reconstruction. Visual analog pain scores (VAS) will be recorded
serially for both sides of the patient's chest in hopes of determining a difference in
duration and efficacy of the two drugs. In addition to VAS scores, a subjective, binary
question will be our primary outcome: does one side of your chest have more surgical pain
than the other? We hope that his question, despite being entirely subjective, overcomes
interpatient variability of numerical pain score reporting.
ultrasound guided PEC II field block injections. The design of the study randomly assigns the
side of injection of the study drugs into each patient. All patients are having bilateral
mastectomy with immediate reconstruction. Visual analog pain scores (VAS) will be recorded
serially for both sides of the patient's chest in hopes of determining a difference in
duration and efficacy of the two drugs. In addition to VAS scores, a subjective, binary
question will be our primary outcome: does one side of your chest have more surgical pain
than the other? We hope that his question, despite being entirely subjective, overcomes
interpatient variability of numerical pain score reporting.
Inclusion Criteria:
- Scheduled for bilateral mastectomy
Exclusion Criteria:
- allergy to local anesthetics, prior breast surgery, asymmetric surgical plan
We found this trial at
1
site
175 Patewood Drive
Greenville, South Carolina 29615
Greenville, South Carolina 29615
Principal Investigator: William Hand, MD
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