Pediatric Urology Recovery After Surgery Endeavor (PURSUE)



Status:Recruiting
Healthy:No
Age Range:4 - 25
Updated:3/30/2019
Start Date:April 1, 2017
End Date:April 30, 2021
Contact:Gino Vricella, M.D.
Email:vricellag@wustl.edu
Phone:314-454-6034

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Multicenter Pilot and Exploration Study of Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Urologic Reconstructive Surgery

The purpose of this research study is to evaluate an Enhanced Recovery After Surgery (ERAS)
protocol in children and young adults undergoing urologic reconstructive surgery. The
investigators plan to collect data on speed of recovery (how quickly pain improves, length of
time in the hospital, and the need for additional pain control) on patients who receive care
under the ERAS protocol and compare it to historical controls.

The purpose of this project is to evaluate Enhanced Recovery After Surgery (ERAS) in the
pediatric setting for participants undergoing intraabdominal urologic reconstruction
procedures. ERAS practices are being implemented in the department independent of research
and this project will allow the investigators to review these practices.

Providers, participants, and family members will complete pre- and post- surgery
questionnaires. These questionnaires are geared to collect demographic information about the
participant and how the surgery affects their life situation. The providers will answer
questions regarding their experience with ERAS.

Evidence-based ERAS principles and procedures are compulsory components of this project.
These will be documented in the medical record and are considered standard of care practice
as part of perioperative patient care.

Data collected from the medical record for each participant will aid in evaluating if
adherence to the ERAS protocol is achieved.

Inclusion criteria:

- Age greater than or equal to 4 or <26 years at time of surgery

- Undergoing urologic reconstructive surgery that includes primary bowel anastomosis
(i.e., creation of continent ileovesicostomy [Monti], sigmoid Monti channel,
enterocystoplasty)

- Undergoing urologic reconstructive surgery that includes possible bowel anastomosis
(planned creation of continent appendicovesicostomy [Mitrofanoff] with inability to
use appendix at time of surgery and creation of alternative channel requiring primary
bowel anastomosis)

Exclusion criteria:

• Clinically constipated (defined as Bristol 1 or 2 stools more than once per week, bowel
movement interval > every other day [e.g. only has bowel movement every 3 days, or palpable
stool in > 50% of colon on physical preoperative exam)
We found this trial at
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sites
4401 Penn Avenue
Pittsburgh, Pennsylvania 15224
412-692-5325
Phone: 412-692-7949
Children's Hospital of Pittsburgh of UPMC UPMC is one of the leading nonprofit health systems...
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3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
 1-513-636-4200 
Phone: 513-803-9093
Cincinnati Children's Hospital Medical Center Patients and families from across the region and around the...
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13123 E 16th Ave
Aurora, Colorado 80045
(720) 777-1234
Principal Investigator: Duncan Wilcox, MD
Phone: 720-777-2678
Children's Hospital Colorado At Children's Hospital Colorado, we see more, treat more and heal more...
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Chicago, Illinois 60614
Phone: 312-227-6340
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Chicago, IL
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660 S Euclid Ave
Saint Louis, Missouri 63110
(314) 362-5000
Phone: 314-454-6034
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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Saint Louis, MO
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